Protein Info for Psest_2415 in Pseudomonas stutzeri RCH2

Annotation: TolQ protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 237 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details amino acids 134 to 155 (22 residues), see Phobius details amino acids 175 to 197 (23 residues), see Phobius details TIGR02796: protein TolQ" amino acids 9 to 224 (216 residues), 256.6 bits, see alignment E=1e-80 PF01618: MotA_ExbB" amino acids 98 to 210 (113 residues), 130.8 bits, see alignment E=1.3e-42

Best Hits

Swiss-Prot: 59% identical to TOLQ_PSEAE: Tol-Pal system protein TolQ (tolQ) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K03562, biopolymer transport protein TolQ (inferred from 97% identity to psa:PST_1946)

Predicted SEED Role

"MotA/TolQ/ExbB proton channel family protein" in subsystem Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GMB5 at UniProt or InterPro

Protein Sequence (237 amino acids)

>Psest_2415 TolQ protein (Pseudomonas stutzeri RCH2)
MQTTLEHMSVWGLISEASLVVQAVMAILVLASVSSWYLIIRRSAALHRSERLLRSFQQRF
RRGGDLAQLYREGQQQPLPEEAALQRIFLAGYGEFAQLQREAGIAPDAIAEGVERSLYVA
IAEQEERLENGLQFLATVGSVSPYIGLFGTVWGIMNSFLGLSQVQQATLSTVAPGIAEAL
IATAIGLFAAIPAVMAYNRFAARGQTLVGRYYAFGNELQARLHRRLHAASPSVAAAA