Protein Info for Psest_2351 in Pseudomonas stutzeri RCH2

Annotation: urea carboxylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1199 PF00289: Biotin_carb_N" amino acids 1 to 110 (110 residues), 145.8 bits, see alignment E=2.6e-46 TIGR02712: urea carboxylase" amino acids 2 to 1197 (1196 residues), 1871.8 bits, see alignment E=0 PF02786: CPSase_L_D2" amino acids 116 to 318 (203 residues), 205.6 bits, see alignment E=2.7e-64 PF07478: Dala_Dala_lig_C" amino acids 147 to 291 (145 residues), 46.4 bits, see alignment E=1.4e-15 PF02785: Biotin_carb_C" amino acids 338 to 446 (109 residues), 102.7 bits, see alignment E=5e-33 TIGR00724: biotin-dependent carboxylase uncharacterized domain" amino acids 455 to 770 (316 residues), 285.5 bits, see alignment E=4.5e-89 PF02626: CT_A_B" amino acids 478 to 751 (274 residues), 317.1 bits, see alignment E=4.4e-98 PF02682: CT_C_D" amino acids 801 to 1019 (219 residues), 138.8 bits, see alignment E=7.9e-44 PF00364: Biotin_lipoyl" amino acids 1137 to 1196 (60 residues), 56.5 bits, see alignment 8e-19

Best Hits

Predicted SEED Role

"Urea carboxylase (EC 6.3.4.6)" in subsystem Urea decomposition (EC 6.3.4.6)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.3.4.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GNB7 at UniProt or InterPro

Protein Sequence (1199 amino acids)

>Psest_2351 urea carboxylase (Pseudomonas stutzeri RCH2)
MFDKLLIANRGAIACRILRTLRGLDVKSVAVYSEADAASLHIQQADEAHSLGEGPAAQTY
LVVEKILRIARETGASAIHPGYGFLSENAAFAEACEAAGIAFVGPTPEQLRMFGLKHTAR
ALAKQRGVPMLEGTELLDSLADALGAAEQVGYPVMLKSTAGGGGIGMRVCRSAAELAEAF
DAVKRLGQNNFSDAGVFIEKYIQRARHLEVQVFGDGRGEVIALGVRDCSVQRRNQKVLEE
TPAPNLPAGMAEALCEAAVKLAKAVSYRSAGTVEFVYDAEAEQFYFLEVNTRLQVEHGVT
EQVWGVDLVRWMIELAAGDLPPLVELARALKSSGHSIQARLYAEDPGRDFQPSPGLLTVV
DFPKGDGKALRIDTWVEAGCEIPPYFDPMVAKLITWAPDRESARAALDTALDETLLYGVE
SNRAYLRQILGYAPFAEGRPWTRCLEGLTYRATTFEVISAGTQTTVQDFPGRLGYWAVGV
PPSGPMDNRALRLGNALLGNPEDAAGLEITMSGPILRFNTDAVVAITGAEIPVKLDDAPQ
PMCTAILVKAGSTLAIGTIVGAGARSYLAVRGGLQVPDYLGSKSTFTLGQFGGHAGRALR
AGDVLHLAPLTDSACGASLPAALCSALPAVRELRVIYGPHGAPEYFTEGYIQTFFATDWE
VHFNSSRTGVRLIGPKPEWVRESGGEAGLHPSNIHDNPYAIGAVDFTGDMPVILGPDGPS
LGGFVCPVTIIEADLWQLGQLKAGDRVRFVPVDVASARQLAQAANIECARLAAAPVPCVP
VALQSPIVLDIGEADTRLVARLSGDTHLLLEIGAPELDLVLRFRGHALMQALEAKQLDGV
IDLTPGIRSLQVHYQPETLALQTLLDIVAGEWDAVCAAQDLKVPSRIVHLPLSWDDPACT
LAIEKYMTTVRKDAPWCPSNLEFIRRINDLPDLDEVYRTVFEASYLVMGLGDVYLGAPVA
TPLDPRHRLVTTKYNPARTWTAENSVGIGGAYMCVYGMEGPGGYQFVGRTLQMWNRYRAV
EAFGGLPWLLRFFDQIRFYPVSAEQLLKIRRDFPLGRYPLKIEQTELRLSDYQDFLAAEA
EGIDAFRRQQRAAFDAERQRWIASGQAHFESEEVAADLGEDAPLGSGLHGIESHIAGNLW
QVSVAEGARVEAGDVLVILESMKMEIPLTAPVAGVVKEVRAQPGSPVRAGQRVVVIEEA