Protein Info for HP15_2252 in Marinobacter adhaerens HP15

Annotation: Na(+)-translocating NADH-quinone reductase subunit B

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 402 transmembrane" amino acids 56 to 77 (22 residues), see Phobius details amino acids 120 to 142 (23 residues), see Phobius details amino acids 154 to 178 (25 residues), see Phobius details amino acids 258 to 280 (23 residues), see Phobius details amino acids 287 to 305 (19 residues), see Phobius details amino acids 317 to 335 (19 residues), see Phobius details amino acids 347 to 365 (19 residues), see Phobius details amino acids 371 to 391 (21 residues), see Phobius details TIGR01937: NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit" amino acids 4 to 398 (395 residues), 587.9 bits, see alignment E=5.5e-181 PF03116: NQR2_RnfD_RnfE" amino acids 41 to 395 (355 residues), 336.6 bits, see alignment E=7.5e-105

Best Hits

Swiss-Prot: 75% identical to NQRB_PSEMY: Na(+)-translocating NADH-quinone reductase subunit B (nqrB) from Pseudomonas mendocina (strain ymp)

KEGG orthology group: K00347, Na+-transporting NADH:ubiquinone oxidoreductase subunit B [EC: 1.6.5.-] (inferred from 94% identity to maq:Maqu_1930)

Predicted SEED Role

"Na(+)-translocating NADH-quinone reductase subunit B (EC 1.6.5.-)" in subsystem Na(+)-translocating NADH-quinone oxidoreductase and rnf-like group of electron transport complexes (EC 1.6.5.-)

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.-

Use Curated BLAST to search for 1.6.5.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PFU6 at UniProt or InterPro

Protein Sequence (402 amino acids)

>HP15_2252 Na(+)-translocating NADH-quinone reductase subunit B (Marinobacter adhaerens HP15)
MAIRQFLDGIEHHFEKGGKYERWYALYEAVDTIFYTPGKVTSTTAHVRDGVDLKRIMITV
WLCTFPAMFFGMWNIGFQANSFLASNPDAMVADGGLRTAFIQALAITGAGAGVWDNFVYG
MAYFVPIYFVTFVVGGFWEVLFATVRRHEVNEGFFVTSVLFALICPPTIPLWQVALGITF
GVVIGKEVFGGTGKNFLNPALTGRAFLYFAYPAQISGDTVWTAVDGFSGATALSWAASGG
LEALEAQIGWMSAFVGTIQGSMGETSTLAVLIGGLILLVMKIASYRIVGGVLIGMIGMSL
LLNIVGSETNPMFAIPAHWHLVMGGFAFGMMFMATDPVSAAMTNTGRWCFGILVGVMTIL
IRVINPAFPEGIMLAILFANLFAPLMDHYVVQANIKRRLARG