Protein Info for PGA1_c22950 in Phaeobacter inhibens DSM 17395
Annotation: Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Predicted SEED Role
"Sulfur carrier protein adenylyltransferase ThiF" in subsystem Thiamin biosynthesis
MetaCyc Pathways
- superpathway of thiamine diphosphate biosynthesis II (8/11 steps found)
- thiazole component of thiamine diphosphate biosynthesis II (5/7 steps found)
- superpathway of thiamine diphosphate biosynthesis I (6/10 steps found)
- thiazole component of thiamine diphosphate biosynthesis I (3/6 steps found)
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See I7E2K5 at UniProt or InterPro
Protein Sequence (587 amino acids)
>PGA1_c22950 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 (Phaeobacter inhibens DSM 17395) MIAELSRWVLAQCPNARDLTQGELSLYEAKDPIHGWVVPFEHQADRFDLQVVLLQDFPWT KPRVYCTEKFRFMQYPHIEKDGAFCLYPPGTEHNPLNPKGLIWDAIKEATRLIVASYDDA FISDFADEFDSYWSKTDGGKNIISLLSPGGPSRRVSLWCSTGDYYLADDHTALESWLRTR FAGNKKDYNFDNATHIVLDRPILPSEYPRSGAAILRFLRELAPKSIELLEDAAVTADDKF TVSFEGRTDDGPVFFAVEVMPPVKQGMKAGRRPDMVQMGFRPGKVPTHIRMQRLFGGNQV ERHETMRADPSWIHGRDTPTVAPLFDKRVLMIGAGSLGSEVALLLAKTGVGSITLVDPEL LDYPNVGRHALGVTQVRTFKAKSLAEKLSGDFPHMHSIEYYPQDWQSLFSERPEVFQNND LIVSTVGSWVAEGRLNQVARNEADFPPVIYGWAEPFSVAGHAVLIGSNGPCFACGMDHLG KALQTVCEWDTETTRKQPHCGASFQPYGPVSLSGVASLVAKTSTKALLGEVHSGTETVYW ASKEEIAEQGGCFTSDFASCFSDVPEFGGTRKFEWRQKEDCAFCAGA