Protein Info for PGA1_c22550 in Phaeobacter inhibens DSM 17395

Annotation: DNA polymerase III beta subunit-like protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 378 PF00712: DNA_pol3_beta" amino acids 21 to 131 (111 residues), 29.2 bits, see alignment E=9e-11 PF02767: DNA_pol3_beta_2" amino acids 143 to 260 (118 residues), 61.6 bits, see alignment E=8.9e-21

Best Hits

Predicted SEED Role

"DNA polymerase III beta subunit (EC 2.7.7.7)" in subsystem DNA-replication (EC 2.7.7.7)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7DSA0 at UniProt or InterPro

Protein Sequence (378 amino acids)

>PGA1_c22550 DNA polymerase III beta subunit-like protein (Phaeobacter inhibens DSM 17395)
MNAHSEIKTDVATKSLKVDISELRAALAWVNKVRETWSRIPILSQNLFQVEGGQLAITAT
CLDREARQTLSCDTSDAWSFVMNGHRVMKVTAGLSGTVTIEHDIAKDLLTLTANGMSLAM
NVMAPPEDWPTTNKQEPLGGIEVGENTLLRALNLVKSCISTEETRYYLNGIYWTSHDGAS
RMVTTNGHRLARLDLEAPNPPFDVIFPRIGITPLAAMLTANGNQLAKITYRGADKTPTLL
SIEMGDRELHCKLIDGTYPDYNRVIPSVDGEQAFDIIIPKSATQRLRLMAGPHDLGCKIS
PEKGTMTIGREDHDGKMSVTYAAKGKSGPDIGFNTLYLAQTTATMGNIRLRAKDNGAPAL
ATSEAHTDLIMVLMPMRV