Protein Info for PGA1_c22100 in Phaeobacter inhibens DSM 17395

Annotation: D-tyrosyl-tRNA(Tyr) deacylase Dtd

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase
  • amino acids 1 to 145 (145 residues), 185.2 bits, E=4.7e-59
• PF02580: Tyr_Deacylase
  • amino acids 2 to 144 (143 residues), 193.1 bits, E=1.5e-61

Best Hits

Swiss-Prot: 72% identical to DTD_PARDP: D-aminoacyl-tRNA deacylase (dtd) from Paracoccus denitrificans (strain Pd 1222)

KEGG orthology group: K07560, D-tyrosyl-tRNA(Tyr) deacylase [EC: 3.1.-.-] (inferred from 72% identity to pde:Pden_1742)

MetaCyc: 52% identical to D-aminoacyl-tRNA deacylase (Escherichia coli K-12 substr. MG1655)
RXN-15041 [EC: 3.1.1.96]; 3.1.1.96 [EC: 3.1.1.96]; 3.1.1.96 [EC: 3.1.1.96]; 3.1.1.96 [EC: 3.1.1.96]; 3.1.1.96 [EC: 3.1.1.96]

Predicted SEED Role

"D-tyrosyl-tRNA(Tyr) deacylase (EC 3.6.1.n1)" (EC 3.6.1.n1)

Isozymes

Compare fitness of predicted isozymes for: 3.1.-.-

Use Curated BLAST to search for 3.1.-.- or 3.1.1.96 or 3.6.1.n1

Sequence Analysis Tools

See I7DS52 at UniProt or InterPro

Protein Sequence (148 amino acids)

>PGA1_c22100 D-tyrosyl-tRNA(Tyr) deacylase Dtd (Phaeobacter inhibens DSM 17395)
MRALIQRVSEASVSVDGETIGDIGPGLLILICAMEGDSEAQADQMATKISKLRIFRDEAG
KMNRSVKDIGGSALVVSQFTLAADTRRGNRPGFSNAAAPELGRALYTRFADQLAALDVPV
ARGSFGADMQVALVNSGPVTIWMDSADW