Protein Info for HP15_2107 in Marinobacter adhaerens HP15

Annotation: cytochrome c oxidase, cbb3-type, subunit I

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 476 transmembrane" amino acids 20 to 42 (23 residues), see Phobius details amino acids 62 to 82 (21 residues), see Phobius details amino acids 94 to 117 (24 residues), see Phobius details amino acids 130 to 151 (22 residues), see Phobius details amino acids 162 to 182 (21 residues), see Phobius details amino acids 205 to 226 (22 residues), see Phobius details amino acids 237 to 255 (19 residues), see Phobius details amino acids 272 to 295 (24 residues), see Phobius details amino acids 307 to 329 (23 residues), see Phobius details amino acids 347 to 367 (21 residues), see Phobius details amino acids 380 to 402 (23 residues), see Phobius details amino acids 435 to 456 (22 residues), see Phobius details TIGR00780: cytochrome c oxidase, cbb3-type, subunit I" amino acids 9 to 473 (465 residues), 750.8 bits, see alignment E=3.2e-230 PF00115: COX1" amino acids 13 to 444 (432 residues), 396.8 bits, see alignment E=6.2e-123

Best Hits

Swiss-Prot: 79% identical to CCON1_PSEST: Cbb3-type cytochrome c oxidase subunit CcoN1 (ccoN1) from Pseudomonas stutzeri

KEGG orthology group: K00404, cb-type cytochrome c oxidase subunit I [EC: 1.9.3.1] (inferred from 95% identity to maq:Maqu_1784)

MetaCyc: 78% identical to cbb3-2 cytochrome c oxidase subunit N (Pseudomonas putida KT2440)

Predicted SEED Role

"Cytochrome c oxidase subunit CcoN (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PRG2 at UniProt or InterPro

Protein Sequence (476 amino acids)

>HP15_2107 cytochrome c oxidase, cbb3-type, subunit I (Marinobacter adhaerens HP15)
MSTVNANLTYNYKVVRQFTIMTVVWGIVGMSLGVLIAAQLVWPSLNLDLPFTHFGRLRPL
HTNAVIFGFGGSALFATSYYVVQRTCQARLISDGLASFTFWGWQAIIVSAAITLPLGLTS
SKEYAELEWPIDIAIAIVWVTYALVFFGTVMKRSTPHIYVANWFYGAFIITVAALHIGNN
LALPASAFKSYSAYAGVTDAMMQWWYGHNAVGFFLTAGFLGMMYYFVPKQANRPVYSYRL
SIVHFWALIATYVWAGGHHLHYSALPDWAQTAGMVMSLILLAPSWGGMINGMMTLSGAWH
KLRTDPILRFLVVSLSFYGMSTFEGPMMAIKTVNALSHNTDWTIGHVHSGALGWVAMISI
GAVYHLVPKLWGVQAMYSSALINVHFWLATVGVVLYIVAMWVNGIMQGLMWRAVNEDGTL
TYSFVEALEASYPGYFVRFIGGAIFVSGMLLMAYNVYMTVRQKDAVAQDNAATQPA