Protein Info for PGA1_c21290 in Phaeobacter inhibens DSM 17395

Annotation: alpha-ketoglutarate-dependent taurine dioxygenase TauD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 278 PF02668: TauD" amino acids 3 to 266 (264 residues), 238.2 bits, see alignment E=8.2e-75

Best Hits

KEGG orthology group: K03119, taurine dioxygenase [EC: 1.14.11.17] (inferred from 55% identity to hne:HNE_0905)

Predicted SEED Role

"Alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.11.17)" in subsystem Alkanesulfonate assimilation or Taurine Utilization (EC 1.14.11.17)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.14.11.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7E278 at UniProt or InterPro

Protein Sequence (278 amino acids)

>PGA1_c21290 alpha-ketoglutarate-dependent taurine dioxygenase TauD (Phaeobacter inhibens DSM 17395)
MDILPMTGGLGAEILGADIRRSEDFSAIRDAFAEYSVIVLRGQTAGPGDHLAFARRFGPV
NVNRFFKPVEGHPEIATVLKEKDQTEAVGEGWHTDHSYDQEPAMGSILHAIEMPPYGGDT
LFVSMGAAYEALSEPMRRFLDGLTAVHSSRHVFGAAAMDSEAVKSGRLGNAEAATQDVRH
PVVITHPLSGRRGLFVNPVFTTRIEGLNPEESSALLAMLYAHCQQPEFQCRVRWRAGDIT
MWDNRATRHKAINDYHGFRRLMHRVTVEGGPLATTPAA