Protein Info for PGA1_c20960 in Phaeobacter inhibens DSM 17395

Annotation: carboxylesterase bioH-like protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 296 transmembrane" amino acids 79 to 96 (18 residues), see Phobius details PF12697: Abhydrolase_6" amino acids 39 to 244 (206 residues), 59.6 bits, see alignment E=1.5e-19 PF12146: Hydrolase_4" amino acids 74 to 240 (167 residues), 38.3 bits, see alignment E=1.9e-13 PF00561: Abhydrolase_1" amino acids 184 to 239 (56 residues), 33.8 bits, see alignment E=5.8e-12

Best Hits

Predicted SEED Role

"Hydrolase, alpha/beta hydrolase fold family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7DRW8 at UniProt or InterPro

Protein Sequence (296 amino acids)

>PGA1_c20960 carboxylesterase bioH-like protein (Phaeobacter inhibens DSM 17395)
MADQQGGAGQTNSARTAERAGGQGIAPLVMLPGLMGTAEVFVPQLRALSGVMPTMVAPLL
GGDRIERIADHLLTQLPGRFALAGLSMGGIVAMEILRRAPERVSRLCLMSTSPLPDTPTQ
AAEWEPLIIAARSGRLEDVLRSCLPVDCLAPSPQRLDILNMIYQQGCTLGSELFVAQARA
LQRRTDQQAALRRFKGPTLILCGAQDRLTPLKRHEFMAALMPNARLRVIEGAGHLPTLEQ
PDQVTGAMAEWLAEVAPRQDARSDPAPDIASAATGEAQSSAPPLPPLTLTNPLKTN