Protein Info for Psest_2062 in Pseudomonas stutzeri RCH2

Annotation: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 254 transmembrane" amino acids 138 to 154 (17 residues), see Phobius details PF00106: adh_short" amino acids 15 to 199 (185 residues), 167.8 bits, see alignment E=3.3e-53 PF08659: KR" amino acids 17 to 168 (152 residues), 36.3 bits, see alignment E=8.2e-13 PF13561: adh_short_C2" amino acids 21 to 250 (230 residues), 216.2 bits, see alignment E=7.8e-68

Best Hits

KEGG orthology group: None (inferred from 94% identity to psa:PST_2263)

Predicted SEED Role

"Glucose 1-dehydrogenase (EC 1.1.1.47)" in subsystem D-gluconate and ketogluconates metabolism or Entner-Doudoroff Pathway (EC 1.1.1.47)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.1.1.47

Use Curated BLAST to search for 1.1.1.47

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GKT3 at UniProt or InterPro

Protein Sequence (254 amino acids)

>Psest_2062 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) (Pseudomonas stutzeri RCH2)
MTDSKHPVIQEVEGKVALVTGAASGIGRAIALLLHERGAKVVAEDINPAVEELARPGLVP
LRADITEDGAAERAVGMAVERFGRLDILVNNAGIIINKLVVDMTRQDWDRIQAVNATAAF
LHCREAVKVMMPNRLGAIVNIASYASYFAFPTIAAYTASKGALAQLTRTLALEAIEHGIR
VNAIGVGDVVTNILNDVVEDGPGFLTQHGQAAPIGRAAQPEEIAEIVAFLASERASFMVG
SVVMADGGMTVTAG