Protein Info for HP15_1946 in Marinobacter adhaerens HP15

Annotation: membrane protein containing DUF6, transmembrane

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 316 transmembrane" amino acids 7 to 24 (18 residues), see Phobius details amino acids 35 to 53 (19 residues), see Phobius details amino acids 69 to 89 (21 residues), see Phobius details amino acids 95 to 114 (20 residues), see Phobius details amino acids 121 to 140 (20 residues), see Phobius details amino acids 148 to 166 (19 residues), see Phobius details amino acids 187 to 206 (20 residues), see Phobius details amino acids 225 to 243 (19 residues), see Phobius details amino acids 255 to 275 (21 residues), see Phobius details amino acids 281 to 302 (22 residues), see Phobius details signal peptide" amino acids 25 to 25 (1 residues), see Phobius details PF00892: EamA" amino acids 7 to 137 (131 residues), 48.8 bits, see alignment E=4.3e-17 amino acids 185 to 296 (112 residues), 34.8 bits, see alignment E=8.8e-13

Best Hits

KEGG orthology group: None (inferred from 74% identity to maq:Maqu_1683)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PQ30 at UniProt or InterPro

Protein Sequence (316 amino acids)

>HP15_1946 membrane protein containing DUF6, transmembrane (Marinobacter adhaerens HP15)
MSDTHKSDLLLVVVTLFAAISWMFSKEAVLLMPPLMFMAARFLIAGTVLAFFARRSLMKL
SVDQLRRSVGVGLVFGTAMTCWVMGLVHITSLGEGAFLTSLGVVIVPIIARLVFKEAQPP
STWLAIPIAVAGLALLSLENGFRPEAGQIFFVMAATIFALYFNLNTRAANQRTVINRLGR
TVEKHRVPALPLTAIALLTVGLLTLVESMIMEPWRPTLNNLSPMLAWWVVASAVIGTAGR
FLLQTFAQSLSANSHGVVILVLEPVWVALFAAGWFGESMTGIQLAGCGLIFAALIVNRWA
VLSKAIKEKLRKRKTA