Protein Info for PGA1_c19970 in Phaeobacter inhibens DSM 17395

Annotation: luciferase family oxidoreductase, group 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 331 PF00296: Bac_luciferase" amino acids 1 to 241 (241 residues), 115.9 bits, see alignment E=1.3e-37 TIGR03558: luciferase family oxidoreductase, group 1" amino acids 4 to 326 (323 residues), 434.2 bits, see alignment E=1.6e-134

Best Hits

Swiss-Prot: 50% identical to YVBT_BACSU: Uncharacterized protein YvbT (yvbT) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 76% identity to sil:SPO2518)

Predicted SEED Role

"Coenzyme F420-dependent oxidoreductase" in subsystem Anaerobic respiratory reductases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EXV9 at UniProt or InterPro

Protein Sequence (331 amino acids)

>PGA1_c19970 luciferase family oxidoreductase, group 1 (Phaeobacter inhibens DSM 17395)
MRYSVLDLAPVPEGQTIAQSLRNSTELAQRAESWGYHRYWLAEHHNMPGIASAATAVLIG
HIAAQTRSIRVGAGGIMLPNHAPYMVAEAFGTLASLHGDRIDLGLGRAPGTDMQTARALR
RGMAHDHASGDSFPQDVIDLMGFLGADDPSRAVRAFPGQDTHVPVWMLGSSLYGAQLAAH
LGLPYAFASHFAPAALEEALEVYRRQFQPSANLSAPHTMMAINVFAAESDDEGRRLRTTM
QQAFARLRLGKPGKLPAPVDDITDHIPAPVLSGVNEALRISATGSKDTVRAELSSILERY
RPDEVIITGQIHDHAARLRSFEIAADILSSV