Protein Info for PGA1_c19830 in Phaeobacter inhibens DSM 17395

Annotation: putative organic solvent tolerance protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 729 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF04453: LptD" amino acids 287 to 653 (367 residues), 169.7 bits, see alignment E=1.3e-53

Best Hits

KEGG orthology group: K04744, LPS-assembly protein (inferred from 64% identity to sil:SPO2455)

Predicted SEED Role

"Organic solvent tolerance protein precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EN32 at UniProt or InterPro

Protein Sequence (729 amino acids)

>PGA1_c19830 putative organic solvent tolerance protein (Phaeobacter inhibens DSM 17395)
MRRALLLSTVLPWLAVAQLATTDVAHAQSAPLGSASAQSSQAPAILVADQLFITPDRTLV
AEGNVEAFQGDIRLTARKITFDQTQGALQIEGPIRIDEGGDITILADAAELDRDLRNGLL
VGARMVFQQQLQLASLQMTRVGGRYTQLYKTAVTSCHVCNDGRPPLWQIRAERITHDQQE
RQLYLENAQLRVLDTPIFYFPGIRLPDPTLERANGFLIPSIRTTSNLGTGVKVPYFLTIG
PHRDLTLSPYLSSRTRTLDMRYRQAFRRGEIEINGAYTRDELYRGEDRGYVFAEGTFDLR
NEFKLRFDLKTVSDDAYLVDYGLRDLDRLRSEVVVSKVQRDSLFRASAISYKTLRDSENQ
DLIPSSIGNLYYERRFFPTQIGGELRLSLETHGHNRTSDIKGNLTDPGGRDVGRATFDVD
WQRSWRFGSGLVAEWSLGAAADAFAVYDDSVFANKTSRFSPRSALTFRLPMTRREQSGAT
QYLEPILQIGWTDTGDTAVPNDESNFVEFDRGNLLELSRFPATDAREDGVTVVYGLNWAR
FSPSGWQASATIGQVFRDSDDGRFTKSSGLGGTSSDLLMAAQLKLNDDLAITTRGLLNGS
FNFSKAEVRGDWMTDRSRLTGTYMWLGTDPAEGRSEEVSELWFDGAYEVTPGWTASASLR
YDISDARATRAGLGLVYSNECVTVDLSVNRRYTSTTSVEPTTDFGFTIALNGFSVDSGSK
KYRRSCKNT