Protein Info for HP15_1892 in Marinobacter adhaerens HP15

Annotation: TPR repeat protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 891 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details PF14559: TPR_19" amino acids 61 to 116 (56 residues), 26.8 bits, see alignment 4e-09 amino acids 163 to 226 (64 residues), 29 bits, see alignment 8.3e-10 amino acids 304 to 352 (49 residues), 29.2 bits, see alignment 7.4e-10 amino acids 511 to 555 (45 residues), 27 bits, see alignment 3.4e-09 PF13432: TPR_16" amino acids 122 to 183 (62 residues), 17.4 bits, see alignment 4.1e-06 amino acids 195 to 252 (58 residues), 29 bits, see alignment 9.5e-10 amino acids 301 to 351 (51 residues), 24 bits, see alignment 3.5e-08 amino acids 657 to 704 (48 residues), 17.8 bits, see alignment 2.9e-06 amino acids 783 to 844 (62 residues), 22.6 bits, see alignment 9.6e-08 PF13429: TPR_15" amino acids 435 to 553 (119 residues), 31.9 bits, see alignment E=7e-11 PF13174: TPR_6" amino acids 501 to 532 (32 residues), 13.2 bits, see alignment (E = 8.9e-05)

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PPX6 at UniProt or InterPro

Protein Sequence (891 amino acids)

>HP15_1892 TPR repeat protein (Marinobacter adhaerens HP15)
MNNVTTLPMFKRHRHHGRVITFCKGLYIGTSLVAALVLAGCGGGSTEPEGLTHINRSETY
AEQGQYRSAMLEIKNAIQQEPENLDYILRLSDLYLRVGAYPEVETLLGPRLDQQPGEIAL
PLAESYIGQGKHLSARETLALADLETPEEKGRGAVVQGGALRLAGDYQAAIEQFEKALAE
GWQVEKATAGILKTYLHLNNPQKAVSEADSYLAEYPESSEVLMLKGRALYTLNRLEPAVE
ALTAAVGALPNSDFFLPVRRQTLTLLSRVLTEQGRVTEAQVYNRVLAENTDSDLENQAKS
AISAIKEGRFDEASETLQDLLQLNPDNERIALTLGALNLQQGRLQEGLDLLSQNIDPETS
PTRFIRLTTMARIDKGERREAYATLARAIEARPDDTELLAMHGMVALSLEDTKSEGVASL
SRALSLNPENVRLRLALANYYEGQGMPEQALGQLRIAFANKPDDWPTTAAYVRLLIREGQ
TGELRELQQSLENGYPENRSAQLLAAISLAGTGDTEEAIKKLEGLRDTNPESIEVNITLA
QLYQEAGQPAKAVNSFVAAAKQTEPKLPLLFRAARLHAANHQNESAVEDWTKSVSQAEPE
LADALAATEILWLISEDELETARSRLAEVGKGIESASLKTAEANLLAAEAQKLTLSEQWD
DAVNKAQQAFALNPENQGFALLPARIRTQQGNIEAAESAVLEVEQVFGATAPVTTARAAI
LQADNRAEEAFQTLYKFWSESGDPAVLPALVQLSNQVAQEKTDELTAKWVDLVPDSVPAN
LSRGNQLMTEGNIMAAANHYQKVLQRDPLHTTALNNLAWALRDTDTPRALEFAARAAEIE
PENPAILDTYGWILHLDGQHRAAMDQLQRALAMAPDNEEFKKHLDEIRRAL