Protein Info for Psest_1909 in Pseudomonas stutzeri RCH2

Annotation: Phosphohistidine phosphatase SixA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 185 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF00300: His_Phos_1" amino acids 60 to 112 (53 residues), 24.8 bits, see alignment E=8.2e-10

Best Hits

KEGG orthology group: None (inferred from 71% identity to psa:PST_2428)

Predicted SEED Role

"putative phosphohistidine phosphatase, SixA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GM96 at UniProt or InterPro

Protein Sequence (185 amino acids)

>Psest_1909 Phosphohistidine phosphatase SixA (Pseudomonas stutzeri RCH2)
MGRAGLLICLLFSLEVAQADDRGGWQALREGRAVLIMRHAAAPGLGDPDGFRLDDCTTQR
NLDERGRAEARQWGVRLRDAGITNARILSSRWCRARDTAEGMALGEVEALPALDSFFALP
ATERRHTAALRQAVGALEPGSVAVLVTHQVNITALTGIFPQSGEGLIVALPLAEPPVILA
RIAPS