Protein Info for Psest_1845 in Pseudomonas stutzeri RCH2

Annotation: ATPase components of ABC transporters with duplicated ATPase domains

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 633 PF00005: ABC_tran" amino acids 19 to 182 (164 residues), 81.4 bits, see alignment E=1.9e-26 amino acids 334 to 467 (134 residues), 87 bits, see alignment E=3.6e-28 PF12848: ABC_tran_Xtn" amino acids 221 to 296 (76 residues), 36.7 bits, see alignment E=7.2e-13 PF16326: ABC_tran_CTD" amino acids 564 to 633 (70 residues), 76.6 bits, see alignment E=2.7e-25

Best Hits

Swiss-Prot: 55% identical to UUP_ECOLI: ABC transporter ATP-binding protein uup (uup) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 94% identity to psa:PST_2485)

Predicted SEED Role

"COG0488: ATPase components of ABC transporters with duplicated ATPase domains" in subsystem Folate Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GK72 at UniProt or InterPro

Protein Sequence (633 amino acids)

>Psest_1845 ATPase components of ABC transporters with duplicated ATPase domains (Pseudomonas stutzeri RCH2)
MTLLKFTDVSLAYGTTPLLDGVSWQIARGERVCIIGRNGTGKSSMLRLVKGDRSADDGEI
WRAPGLKIGELPQELPRADDRTVFDVVAEGLAGVGELLAEYHHLSQNIQDEADLEKLMHV
QQALEAKDGWRLQQLVDSTLSRLQLPADRTLAELSGGWRRRVLLAQALVSEPDLLLLDEP
TNHLDIGAIAWLEEALTGFNGAVLFITHDRAFLQNLATRILELDRGHLIDWNGDYASFLV
HKEQQLAAEETANALFDKKLAQEEVWIRQGIKARRTRNEGRVRALKALRAERSERRNVQG
KATFQVETAEKSGKQVIVAEQVTFAHVGGEPLIRDFSMVIQRGDRIGLLGANGTGKTTLL
KLLLGELHPSSGSIEFGTKLEVAYFDQLRHQLELEKTVVDNLAEGREFITIDGQNRHVLS
YLGDFLFSPQRARTPVKALSGGERARLLLAKLFSKPANLLVLDEPTNDLDVETLELLEEV
LLGFQGTVLMVSHDRAFLDNVVTSTLVFQGGGEVREYVGGYQDWLRQGGSPRLLGVAESG
GEAKKAQQAPVAAVVAEVAPAKKKLSYKLQRELEALPGQIDEAEKAIEALQAEISDPAFY
QQAADKTAAVLSRLEALQAELDGLLERWAELEE