Protein Info for Psest_1841 in Pseudomonas stutzeri RCH2

Annotation: lipid kinase YegS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 303 TIGR03702: lipid kinase YegS" amino acids 5 to 296 (292 residues), 435.1 bits, see alignment E=1e-134 PF00781: DAGK_cat" amino acids 6 to 124 (119 residues), 87.4 bits, see alignment E=6.2e-29 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family" amino acids 7 to 291 (285 residues), 184.1 bits, see alignment E=2.9e-58 PF19279: YegS_C" amino acids 146 to 287 (142 residues), 47.3 bits, see alignment E=1.9e-16

Best Hits

Swiss-Prot: 70% identical to YEGS_PSEAE: Probable lipid kinase YegS-like (PA3023) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K07029, (no description) (inferred from 87% identity to psa:PST_2489)

Predicted SEED Role

"Transcription regulator [contains diacylglycerol kinase catalytic domain]"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GKR8 at UniProt or InterPro

Protein Sequence (303 amino acids)

>Psest_1841 lipid kinase YegS (Pseudomonas stutzeri RCH2)
MSDAKALLILHGKQALNDEVREAVRQQRDYGWDLAVRVTWEPGDAQRLVAEALDAGYSKL
VAGGGDGTLREVAEAMLQAQAQASLALMPLGSANDFAKAAGIPLDPFEALGLLDEPARWV
DVGEMNGQPFVNMATGGFGSKVTASTSEDLKRVLGGGAYLLTGLTRFAEIHSARGRFTGP
GFDWEGEFLALGIGNGRQAGGGQLLCPQAKIDDGLLDVCIVPAPADAVGTLGTLLSGGLL
GVDAVSVSARVPWLEVEAPSAIDINLDGEPSTAAHLRFDVRAGALRLHLPADCPLLGPAS
SAP