Protein Info for Psest_0175 in Pseudomonas stutzeri RCH2

Annotation: Xaa-Pro aminopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 444 PF05195: AMP_N" amino acids 9 to 128 (120 residues), 135 bits, see alignment E=1.1e-43 PF00557: Peptidase_M24" amino acids 183 to 414 (232 residues), 223.5 bits, see alignment E=2.6e-70

Best Hits

KEGG orthology group: K01262, Xaa-Pro aminopeptidase [EC: 3.4.11.9] (inferred from 97% identity to psa:PST_4070)

Predicted SEED Role

"Xaa-Pro aminopeptidase (EC 3.4.11.9)" (EC 3.4.11.9)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.11.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GFH9 at UniProt or InterPro

Protein Sequence (444 amino acids)

>Psest_0175 Xaa-Pro aminopeptidase (Pseudomonas stutzeri RCH2)
MTRIPRSEYARRRKALMEQMEPNSIAILPAAPMYIRNRDVEHVYRQDSDFQYLSGFPEPE
AVIALIPGREHGEYVLFCRERDPERELWDGLRAGQDGAIAEYGADDAFPIGDIDDILPGL
IEGRDRVYYAIGTNEAFDHRLMEWIKTIRGKARQGAQPPSEFVALDHLLHDMRLFKSSNE
VKVMKHAAEISARAHIRAMQASRAGLFEYHLEAELDYEFRKGGAKMPAYGSIVAVGRNAC
ILHYRENDAPLKDGDLVLIDAGCEIDCYASDITRTFPVNGRFSPEQKAIYELVLKANEEA
FKHIAPGKHWNEAHEATVRVITAGLVELGLLQGEVDALIASEAYKAFYMHRAGHWLGMDV
HDVGDYKIGGEWRVLEPGMAMTVEPGIYIAVDNQSVAKKWRGIGVRIEDDVVVTRTGCEI
LTTGVPKSVAEIEALMAAAREQVA