Protein Info for PGA1_c17080 in Phaeobacter inhibens DSM 17395

Annotation: pyruvate ferredoxin/flavodoxin oxidoreductase-like protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1139 PF02775: TPP_enzyme_C" amino acids 455 to 572 (118 residues), 23.4 bits, see alignment E=6.8e-09 PF01558: POR" amino acids 716 to 909 (194 residues), 77.1 bits, see alignment E=2.7e-25 PF20169: DUF6537" amino acids 933 to 1122 (190 residues), 181.7 bits, see alignment E=2.5e-57

Best Hits

KEGG orthology group: K04090, indolepyruvate ferredoxin oxidoreductase [EC: 1.2.7.8] (inferred from 70% identity to jan:Jann_2176)

Predicted SEED Role

"Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits" in subsystem Aromatic amino acid interconversions with aryl acids

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.2.7.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7E124 at UniProt or InterPro

Protein Sequence (1139 amino acids)

>PGA1_c17080 pyruvate ferredoxin/flavodoxin oxidoreductase-like protein (Phaeobacter inhibens DSM 17395)
MSTQKISLNDKFDLTKSQVMLNGTQALVRLMLMQKHRDKAAGLNTAGLVTGYRGSPLGAV
DMQMKRAEKHLTASDVTFQFGLNEDLAVTALWGAQQAEVRGEGKYDGVFGLWYGKGPGVD
RSGDAIRHANMAGSSKHGGVLVAMGDDHTGESSTVLHQSEWSLMDCYLPIVSPAGVQEIL
DYGAYGLALSRFSGLWVGLKTMKDTIEVTSVVDGDPDRMKLVTPEFDMPADGLNIRLDDD
RFRQENRIIDYKRFAAEAFSHANKMDKRMWGKPGAKIGFVAAGKNWLDLVHAMSLLNIDE
TMAERLGITTYKVGQTWPLDMKGFNDWAEGLDLIVVVEEKRKLIEIQIKEAIFDDRQGRR
VYGWYKGGAGAMHREELFPTKYALDPIMIAEKLGQILIEEGRETEAIRAGLTALDDAKRA
DNAEEIAARLPYFCSGCPHNSSTKLPDGSRAYAGIGCHFMVQWMDRETTGFTHMGGEGVN
WVGEAPFSNRKHVFQNLGDGTYNHSGVQAIRAALAEGTNITFKILYNDAVAMTGGQEAEG
GLTAHQIAHELTAMGMKTIAVVYDEKEDVDAKLFPAGMRMHERAELMAVQKEMETVEGVS
AIIYIQTCAAEKRRRRKKGLFPDPDQRVFINSDVCEGCGDCGVQSNCVSIVPKETELGRK
RAIDQSSCNKDFSCVKGFCPSFLTIEGAKIRKEPTAALDLPDLPKPELPSINGTHNVVIT
GVGGTGVVTIGAVLAQAAQIDGKGAGMMEMAGLAQKGGAVHIHCRIANKPEDISAIRVAT
GEAHALIGGDLVVSAGAKTIGLMKTGKTGAVVNSHEIITGDFTRDTDFQLPTDRLQVALE
ARLRDRLDLFDASDLARASMGDSIFSNMMIFGAAWQRGLLPISLEAIQEAITLNGAAVER
NLRAFDIGRWAVLYPQEVQKLIAPNVVELPKSLEEQIAFRSAQLVDYQGPRLAKRYGKML
DGIADKALKESVAKGYHKLLSYKDEYEVARLLLSSREKAEAEFEGDLKISYNLAPPMLTG
KDPDGRPKKRKFGPGLERGLRLLAKFKGLRGTPLDVFGYTAERKMERALIAQYEADMKEW
LPKASPEIMAPLIALAELPLEIRGFGPVKQANESKAAKRREELLAALRHGGTELKTAAE