Protein Info for PGA1_c16940 in Phaeobacter inhibens DSM 17395

Annotation: lexA repressor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 224 PF01726: LexA_DNA_bind" amino acids 2 to 63 (62 residues), 53.4 bits, see alignment E=1.7e-18 TIGR00498: repressor LexA" amino acids 2 to 223 (222 residues), 185.2 bits, see alignment E=5.4e-59 PF00717: Peptidase_S24" amino acids 102 to 218 (117 residues), 123.4 bits, see alignment E=4.1e-40

Best Hits

Swiss-Prot: 71% identical to LEXA_ROSDO: LexA repressor (lexA) from Roseobacter denitrificans (strain ATCC 33942 / OCh 114)

KEGG orthology group: K01356, repressor LexA [EC: 3.4.21.88] (inferred from 71% identity to rde:RD1_3216)

Predicted SEED Role

"SOS-response repressor and protease LexA (EC 3.4.21.88)" in subsystem DNA repair, bacterial (EC 3.4.21.88)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.21.88

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EZK0 at UniProt or InterPro

Protein Sequence (224 amino acids)

>PGA1_c16940 lexA repressor (Phaeobacter inhibens DSM 17395)
MLTKKQLDLLDFINTRLQQDGVPPSFDEMKVALDLRSKSGIHRLITALEERGFIRRLAHR
ARAIEIIRLPDSLGNTAEAAPAAPGPANQVSAPAMIAAMELPVMGRIAAGVPIEAINQVS
HQVAVPASMLSAQGQHFALEVRGDSMIEAGINDGDIVVIRETAVADNGDVVVALVEGQEA
TLKRIYRKGSTIALEAANPAYETRRYPQDQVKVQGRLVGLIRTY