Protein Info for HP15_1560 in Marinobacter adhaerens HP15

Annotation: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 777 signal peptide" amino acids 1 to 39 (39 residues), see Phobius details PF20256: MoCoBD_2" amino acids 54 to 184 (131 residues), 63.1 bits, see alignment E=3.2e-21 amino acids 640 to 724 (85 residues), 70.5 bits, see alignment E=1.8e-23 PF02738: MoCoBD_1" amino acids 342 to 571 (230 residues), 99.4 bits, see alignment E=1.7e-32

Best Hits

Predicted SEED Role

"Isoquinoline 1-oxidoreductase beta subunit (EC 1.3.99.16)" in subsystem N-heterocyclic aromatic compound degradation (EC 1.3.99.16)

Isozymes

Compare fitness of predicted isozymes for: 1.3.99.16

Use Curated BLAST to search for 1.3.99.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PLB6 at UniProt or InterPro

Protein Sequence (777 amino acids)

>HP15_1560 aldehyde oxidase and xanthine dehydrogenase molybdopterin binding protein (Marinobacter adhaerens HP15)
MSADDNLMIANVSRRRFLMGLAGGSALVLAARWDVALAGNEKAQFGAGAMPGGWVDDPNV
FIHIDADGLVTIVNNRSEMGQGIRTSLVMVGADELGADWDQVRVEQAEGDHDKYGNQNTD
GSRSMRHWYQPMRRAAAAARQMLEQAAANEWGVPVSEVQAGVHTIVHRPSGKELGFGELA
AKARELDVPGRNALVLKRDDELRFVGKETGLINGELKSAYPKAIDGEDIVTGKAVYGADV
PFEGLLYAVIARPPVYGATVGDFDDTEALKVPGVEKVLKVEGTGQPAGFSPLGGIAVVAS
NTWAAMEGRKALKIDWNLEPAGDNASYTSATYRESLEKAAQQPGKVVRQHGDLDTALENA
DKRVSATYYMPHMAQAPMEPPVATVRIKDGKAEVWAPVQNPQATRDTVAGRLGLDAENVT
VHVTLLGGGFGRKSKPDFAIEAASIAEAFKGRPVRLQWSREDDIHHAYYHAVSVDYLEAG
LDNNGQATGWLHRTLSPSIGSLFAPDPKHKGEFELGMGFNTMPFSVPALRLENPPAPAHV
RIGWFRSVYNLPHAWAIQSFAHEMAVAAGKDHRDYVLDLLGPDREIHNLTVGDGWNYGED
PDLYPIDIGRMRNVIERVTREADWGKSTGKNRGLGLAFHHSFVSYTAIVFDVEVDDQGEL
TIHRADIAFDCGPQANPERIRSQLEGAIVMGIGIALQSEVTFEDGVAQQGNFDKYLIPRM
PDAPKTLRVHLVDNPDEAMGGVGEPGLPPVAPALCNAIYAATGKRIRRLPVGDQLKA