Protein Info for PGA1_c13940 in Phaeobacter inhibens DSM 17395

Annotation: ADP-ribose pyrophosphatase-like protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF06094: GGACT
  • amino acids 4 to 107 (104 residues), 43.5 bits, E=4.6e-15
• TIGR00052: nudix-type nucleoside diphosphatase, YffH/AdpP family
  • amino acids 184 to 362 (179 residues), 110.5 bits, E=3.8e-36
• PF00293: NUDIX
  • amino acids 223 to 342 (120 residues), 61.3 bits, E=1e-20

Best Hits

KEGG orthology group: None (inferred from 55% identity to sil:SPO1920)

Predicted SEED Role

"Tellurite resistance protein TrgB / ADP-ribose pyrophosphatase (EC 3.6.1.13)" in subsystem NAD and NADP cofactor biosynthesis global or Nudix proteins (nucleoside triphosphate hydrolases) (EC 3.6.1.13)

KEGG Metabolic Maps

• Purine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.1.13

Sequence Analysis Tools

See I7ELJ0 at UniProt or InterPro

Protein Sequence (374 amino acids)

>PGA1_c13940 ADP-ribose pyrophosphatase-like protein (Phaeobacter inhibens DSM 17395)
MVDLFVYGTLRHLPLLELVLGRSGAALDAAPAHLPDHGAFAVVDQPFPAIEARAGHRAPG
LLLRGLTQNDIDALNFYEGGFDYKLRRVTVELDAGGSAPADVYFPDPGLWQTGDPWDLAA
WQADWGALSLHAAEEVMAYRGRLTPAEVAARFRPIRVRAAAWLAAQNRPEDPDHDLTRDV
VVHEHKRAYVNFFAMEEMDLQFRRYDGSLSPVVNRGAALVGQAAVVLPYDPRRDAVLLIE
QFRAATYIAGNRRPWMWEPVAGLIDPGETPEQAAHREAMEEAGLTIDKLETVAQVYPSSG
ASGEFLHIFVGVCDFENIAGGGGLESENEDIRSQIIPYDDLMRGIDDHSYQDMPLVTAAL
WLSRHRDRLRHRER