Protein Info for HP15_1339 in Marinobacter adhaerens HP15

Annotation: cupin 2 conserved barrel domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 121 PF07883: Cupin_2" amino acids 38 to 97 (60 residues), 42.6 bits, see alignment E=2e-15

Best Hits

KEGG orthology group: None (inferred from 72% identity to pct:PC1_1138)

Predicted SEED Role

"Mannose-6-phosphate isomerase (EC 5.3.1.8)" in subsystem Alginate metabolism or Mannose Metabolism (EC 5.3.1.8)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.3.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PIM8 at UniProt or InterPro

Protein Sequence (121 amino acids)

>HP15_1339 cupin 2 conserved barrel domain protein (Marinobacter adhaerens HP15)
MGYQAINFKNKLGLFDEQWSPKVIAEMNDYQFKVVKIQGEFVWHDHKDTDETFIVLEGSL
RINFRDGHVDLSEGEMYVVQKGVEHKPFAEHEAKVLLIEPRGVVNTGDETGTQTAENDVW
I