Protein Info for Psest_1288 in Pseudomonas stutzeri RCH2

Annotation: Putative multicopper oxidases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 456 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF07732: Cu-oxidase_3" amino acids 55 to 159 (105 residues), 110.1 bits, see alignment E=7.2e-36 PF07731: Cu-oxidase_2" amino acids 353 to 455 (103 residues), 95 bits, see alignment E=3.5e-31

Best Hits

KEGG orthology group: None (inferred from 94% identity to psa:PST_3006)

MetaCyc: 71% identical to CumA multicopper oxidase (Pseudomonas putida GB-1)

Predicted SEED Role

"Multicopper oxidase" in subsystem Copper homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GIM1 at UniProt or InterPro

Protein Sequence (456 amino acids)

>Psest_1288 Putative multicopper oxidases (Pseudomonas stutzeri RCH2)
MSFTRRQILTGLAGLGVVGLAGSGARYWLGRPADITTHDYELIAAPLDVELVPGHVTPAW
AYGGQAPGLELRGRQGDWLRVRFINNLPEPTTIHWHGIRLPLEMDGVPYVSQLPVLPGEF
FDYRFQLHDAGSFWYHPHTSSAAQLGRGLVGPLIVEEREPSGFRHERTLSLKSWHIDKQG
AFTEFSVPREAARGGTPGVLSTVNGTHAPTLDLPAGQVVRLRVLNLDNTLTYRLNLPDGE
ARIYALEGHPIAPMPLGKEYWLGPGMRIDLALKVPEVGTELSLRNGPLRLATLRSVAHDE
TAGDWPPALPTNPVAEPDLQRAETLRFNFEWAGTLSTDAEQGGAYTFWQINGQAWDINDK
SCAERPIATLKRDGHYIFELRNLSQYQHPIHLHGMTFKVISSNRRKIDPWFTDTYLLGKN
ETARIALVADNPGVWMFHCHVIDHMETGLMAAIEVV