Protein Info for PGA1_c01240 in Phaeobacter inhibens DSM 17395

Annotation: electron transfer flavoprotein subunit alpha

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 308 signal peptide" amino acids 1 to 16 (16 residues), see Phobius details PF01012: ETF" amino acids 4 to 170 (167 residues), 115.3 bits, see alignment E=2.9e-37 PF00766: ETF_alpha" amino acids 189 to 269 (81 residues), 126 bits, see alignment E=4.6e-41

Best Hits

Swiss-Prot: 80% identical to ETFA_PARDE: Electron transfer flavoprotein subunit alpha (etfA) from Paracoccus denitrificans

KEGG orthology group: K03522, electron transfer flavoprotein alpha subunit (inferred from 90% identity to sit:TM1040_2426)

Predicted SEED Role

"Electron transfer flavoprotein, alpha subunit" in subsystem Acetyl-CoA fermentation to Butyrate

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EVP9 at UniProt or InterPro

Protein Sequence (308 amino acids)

>PGA1_c01240 electron transfer flavoprotein subunit alpha (Phaeobacter inhibens DSM 17395)
MAVLLLAEVTDGALALDATAKAVTAAGKLGDVTVLAAGASAAAAGEEAAKIAGVAKVLVA
EDASLGHRLAEPTAALIASLASDYEHIVAPATTDAKNVLPRVAALLDVMVISDVSGVVDG
DTFERPIYAGNAVQTVKSRDAKKVISFRTSTFDAAGDGGSASVDTISAAENPGLSEWVED
KVAASDRPELTSAGVVVSGGRGVGSEEDFKLIESLADKLGAAVGASRAAVDSGYAPNDWQ
VGQTGKVVAPELYVAVGISGAIQHLAGMKDSKIIVAINKDEEAPIFQVADYGLVADLFQA
VPELIEKL