Protein Info for HP15_1128 in Marinobacter adhaerens HP15

Annotation: glutamate synthase domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 554 transmembrane" amino acids 20 to 37 (18 residues), see Phobius details amino acids 43 to 60 (18 residues), see Phobius details PF01645: Glu_synthase" amino acids 165 to 482 (318 residues), 275.2 bits, see alignment E=4.8e-86

Best Hits

KEGG orthology group: None (inferred from 88% identity to maq:Maqu_2046)

Predicted SEED Role

"Ferredoxin-dependent glutamate synthase (EC 1.4.7.1)" in subsystem Ammonia assimilation or Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis (EC 1.4.7.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.4.7.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PGV6 at UniProt or InterPro

Protein Sequence (554 amino acids)

>HP15_1128 glutamate synthase domain protein (Marinobacter adhaerens HP15)
MRQPEDSMEKTKTFPLRYSAYALSIIGFFVSFGLVMFADVSLAFPLIFGAFAALGTYDLL
QRRHTVSRNYPILANFRYLLESVGPEIRQYFIQSDTEERPFSREQRTIVYQRAKNVLDKR
PFGSQLGMYDEGFEWMNHSLAPTRLDSSDFRILIGRNCDKPYNASVFNISAMSFGSLSAN
AILSLNTGARMGGFYHDTGEGSISRYHRQPGGDLVWEIGSGYFGCRHKDGSFNEDMFRQN
ATIEQVKMIELKLSQGAKPGHGGILPGAKVTPEIAEARGVSVGEDCVSPASHSAFSTPIE
MLEFIDRLRELSGGKPVGFKLAIGHPWEWFAIVKAMLETGRKPDFIVVDGGEGGTGAAPL
EFINRLGMPMTEALLLVHNTLVGTHLREDIAIGAAGKITSAFNIARTLALGADWCNAARG
YMFSLGCIQALSCHTGRCPSGVATQDPRRGNKLDVELKSRRVYNYHKNTLDALQNLLEAS
GLKHPSELGPEHVVRRVSKTEVHSYMDLFPFLEPGALLEGKTDLTVFDKYWESARADTFE
PPEFILKLRETKLR