Protein Info for Psest_1119 in Pseudomonas stutzeri RCH2

Annotation: uracil-xanthine permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 419 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 38 to 54 (17 residues), see Phobius details amino acids 60 to 77 (18 residues), see Phobius details amino acids 83 to 103 (21 residues), see Phobius details amino acids 114 to 136 (23 residues), see Phobius details amino acids 152 to 173 (22 residues), see Phobius details amino acids 181 to 208 (28 residues), see Phobius details amino acids 223 to 248 (26 residues), see Phobius details amino acids 303 to 325 (23 residues), see Phobius details amino acids 331 to 352 (22 residues), see Phobius details amino acids 364 to 381 (18 residues), see Phobius details amino acids 387 to 405 (19 residues), see Phobius details TIGR00801: uracil-xanthine permease" amino acids 10 to 403 (394 residues), 366.4 bits, see alignment E=9.8e-114 PF00860: Xan_ur_permease" amino acids 11 to 379 (369 residues), 309.2 bits, see alignment E=1.8e-96

Best Hits

Swiss-Prot: 59% identical to URAA_PASMU: Probable uracil permease (uraA) from Pasteurella multocida (strain Pm70)

KEGG orthology group: K02824, uracil permease (inferred from 97% identity to psa:PST_3176)

MetaCyc: 38% identical to uracil:H+ symporter UraA (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-132

Predicted SEED Role

"Uracil permease" in subsystem De Novo Pyrimidine Synthesis or Pyrimidine utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GG16 at UniProt or InterPro

Protein Sequence (419 amino acids)

>Psest_1119 uracil-xanthine permease (Pseudomonas stutzeri RCH2)
MSHTDEPLGRQVLAGAQMLFVAFGALVLMPLITGMDPNVALFTAGLGTLLFQVITRRQVP
VFLASSFAFIAPIIAAKGEFGLPAVMGGVVAAGLVYMLLGFAVRLKGPGFIDRLLPPVVI
APVIISIGLALSPVAVNMAMGKAGDGSAQLIPYQTAMLISMPALVTTLLVAVLGKGLFRL
VPILAGVAVGYGLSFAFGVVDTSGIAAAPWLAMPNFVAPEFNIGAILFMVPVALAPAIEH
IGGVVAIGSVTGNNYVKKPGLHRTLLGDGVATSAAGLFGGPPNTTYAEVTGAVMLTKNYN
PKIMTWAAVFAIALAFIGKFGAGLLSIPVPVMGGILCLLFGSIAVVGLSTLIRHQVDLSE
ARNLIIVSVTLVFGIGGMAIGYGEFTLSGISLCAIIALLLNLLLPGGEGWRNKQLNEEP