Protein Info for PGA1_c01070 in Phaeobacter inhibens DSM 17395

Annotation: GTP-binding protein Era

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 301 TIGR00436: GTP-binding protein Era" amino acids 6 to 278 (273 residues), 235.6 bits, see alignment E=6.5e-74 TIGR00231: small GTP-binding protein domain" amino acids 6 to 165 (160 residues), 75.8 bits, see alignment E=3.3e-25 PF10662: PduV-EutP" amino acids 8 to 167 (160 residues), 21.6 bits, see alignment E=5.6e-08 PF01926: MMR_HSR1" amino acids 8 to 124 (117 residues), 80.6 bits, see alignment E=3.4e-26 PF02421: FeoB_N" amino acids 8 to 163 (156 residues), 43.7 bits, see alignment E=7.3e-15 PF00009: GTP_EFTU" amino acids 43 to 172 (130 residues), 33.2 bits, see alignment E=1.4e-11 PF07650: KH_2" amino acids 207 to 284 (78 residues), 65.1 bits, see alignment E=1.5e-21

Best Hits

Swiss-Prot: 81% identical to ERA_DINSH: GTPase Era (era) from Dinoroseobacter shibae (strain DSM 16493 / NCIMB 14021 / DFL 12)

KEGG orthology group: K03595, GTP-binding protein Era (inferred from 87% identity to sit:TM1040_2558)

Predicted SEED Role

"GTP-binding protein Era" in subsystem Bacterial Cell Division or Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EIC0 at UniProt or InterPro

Protein Sequence (301 amino acids)

>PGA1_c01070 GTP-binding protein Era (Phaeobacter inhibens DSM 17395)
MTTRAGFVALIGEPNAGKSTLLNRMVGAKVSIVTHKVQTTRARIRGVAMEGESQIVFVDT
PGLFQPRRRLDRAMVAAAWGGAADADVVVLMVEAHRGITEGVERILEGLENIGEGRKIAL
AINKIDRVQSAVLLGLTKDLNERYAFADTFMISAEKGHGVDHLRGWLAEQLPEGPWLYPE
DQIADLPMRMIAAEMTREKLTLRLHQELPYQLTVETENWEERKDGSAKIDQLIYVMRDGH
KGIVLGKRGETIKAVSQAARAELEEFLDRKVHLFLQVKVRPNWLEESERYSEMGLDFKDG
N