Protein Info for EX31_RS14035 in Rahnella sp. WP5

Annotation: vitamin B12 ABC transporter permease BtuC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 335 transmembrane" amino acids 21 to 40 (20 residues), see Phobius details amino acids 65 to 83 (19 residues), see Phobius details amino acids 95 to 114 (20 residues), see Phobius details amino acids 120 to 141 (22 residues), see Phobius details amino acids 153 to 173 (21 residues), see Phobius details amino acids 197 to 220 (24 residues), see Phobius details amino acids 240 to 270 (31 residues), see Phobius details amino acids 282 to 301 (20 residues), see Phobius details amino acids 310 to 329 (20 residues), see Phobius details PF01032: FecCD" amino acids 29 to 330 (302 residues), 292.3 bits, see alignment E=2e-91

Best Hits

Swiss-Prot: 71% identical to BTUC_SERP5: Vitamin B12 import system permease protein BtuC (btuC) from Serratia proteamaculans (strain 568)

KEGG orthology group: K06073, vitamin B12 transport system permease protein (inferred from 100% identity to rah:Rahaq_2827)

MetaCyc: 64% identical to vitamin B12 ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
ABC-5-RXN [EC: 7.6.2.8]; 7.6.2.8 [EC: 7.6.2.8]

Predicted SEED Role

"Vitamin B12 ABC transporter, permease component BtuC" in subsystem Coenzyme B12 biosynthesis

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (335 amino acids)

>EX31_RS14035 vitamin B12 ABC transporter permease BtuC (Rahnella sp. WP5)
MPIPQTFSAFEQQQKYRDRRWLYGLGMFLLLIWVFSLSAGERWLWPDQWLSTEARLFVWQ
LRFPRAVAVILVGASLAVSGAVMQSLFENPLAEPGLLGVANGACVALVLCVMLSHGLLPV
WIMSLAAIAGALIVTFFLLYIARKRLLTNARMLLVGIAIGIVCSALMTWAIYFSNNLDLR
QLMYWMMGGFGGVDWNQLWLGLMLLPVLLWLVLQGNALNLLSLGTQQARQLGISLNTWRY
ILVLAVGWMVGLSVALSGVIGFIGLIIPHILRLCGITDQRRLLPACALCGASVLLLADVL
ARIGLSAAELPIGVVTATLGAPVFIWLLTRTGQIR