Protein Info for EX31_RS11185 in Rahnella sp. WP5

Annotation: MBL fold metallo-hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 278 PF00753: Lactamase_B" amino acids 53 to 246 (194 residues), 80.9 bits, see alignment E=1.9e-26 PF12706: Lactamase_B_2" amino acids 66 to 224 (159 residues), 36.1 bits, see alignment E=8.4e-13

Best Hits

KEGG orthology group: None (inferred from 100% identity to rah:Rahaq_1870)

Predicted SEED Role

"beta-lactamase domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (278 amino acids)

>EX31_RS11185 MBL fold metallo-hydrolase (Rahnella sp. WP5)
MNVNFPTRDLGDISVTAVSDGYLHVDFGMLSNVDEDECKEIQRSAQVSELNAVHINTFLV
RQKGKNILIDSGAGGVKGWGGKLVANLDLLGIQPGNIDAVLLTHAHPDHIGGLLNAEGEA
VFANAELIINSDEFNYLQDDENFAAVSDRVKGNFLLARSIFKKYQKNLRLIDKGEVFPGV
FAIPLKGHTPGHTGYRIEGNRDSLLIWGDIVHFPHIQLLKPDVAIAFDYDPQMAAETRSR
ILESVSSDSVLVGGMHFGEQGFGYIEKRKSGYVTVDIH