Protein Info for EX31_RS09805 in Rahnella sp. WP5
Annotation: transcriptional regulator LsrR
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 76% identical to LSRR_PHOLL: Transcriptional regulator LsrR (lsrR) from Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)
KEGG orthology group: K11531, lsr operon transcriptional repressor (inferred from 100% identity to rah:Rahaq_2587)Predicted SEED Role
"LsrR, transcriptional repressor of lsr operon" in subsystem Autoinducer 2 (AI-2) transport and processing (lsrACDBFGE operon)
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (324 amino acids)
>EX31_RS09805 transcriptional regulator LsrR (Rahnella sp. WP5) MNEKTTLSDLTNHPEFSMGEEELLARTAWFYYHDGLTQNEIGERLGLTRLKVSRLLEKGR QSGVIRVQINSRFEGCLTLENTLLERFGLQQIRVLPQLADGSLSTRLGVGAAHMLMTLLR PEQLLAVGFGETAMSTLQHLSGFISSQQIRMVTLSGGVGPYMTGIGQLDAACGVSIIPAP LRASSASVAAIFRQERNVHDVMLAACAADIAVVGIGSLNQKQDATILRSGYISEGEQLLF GRKGAVGDILGFFMQRNGELAENMAIHDELIAVAPDELASIPTVLGVAGGVEKAEAIVAA LKGKRINALVTEESTARAMLALLD