Protein Info for EX31_RS00270 in Rahnella sp. WP5

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 717 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF07715: Plug" amino acids 58 to 168 (111 residues), 81.9 bits, see alignment E=7.1e-27 PF00593: TonB_dep_Rec" amino acids 245 to 679 (435 residues), 197.5 bits, see alignment E=1.1e-61 PF14905: OMP_b-brl_3" amino acids 414 to 691 (278 residues), 47.7 bits, see alignment E=1.9e-16

Best Hits

Swiss-Prot: 63% identical to YNCD_ECOLI: Probable TonB-dependent receptor YncD (yncD) from Escherichia coli (strain K12)

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 100% identity to rah:Rahaq_4777)

MetaCyc: 63% identical to pyrroloquinoline quinone outer membrane transporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-629

Predicted SEED Role

"Probable tonB-dependent receptor yncD precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (717 amino acids)

>EX31_RS00270 TonB-dependent receptor (Rahnella sp. WP5)
MNAKTSAFIITFLSFFNPVSVSYAQSSTASPKDDAGDTAGSSTMMVIKRESTGKLSELDT
PAAVSVIDGGDFRNSKAQVNLSESLGSVPGLQVQNRQNYAQDLQLSVRGFGSRSMYGVRG
VRIYVDGIPATMPDGQGQTSNIDLNSVERVEVLRGPFSALYGNASGGVVNVDTQTGSQPA
KLEAGTYFGSYGSFRNSVKASGATGDGTHAGDVNYLISGSRFTTDGYRDHSGTQKNLGNG
KLGVRIDDDSTLTLMFNSVSVDANDPGGLTESEWHDDPKQAKRADQYNARKSLDQTQVGL
RYQRQMGENDEFSLMTYHGERHTTQYQTIPAASQKNPLNAGGVIVLERKYSGVDTRWKHD
DQIGSVPFSVTGGLDYETMTERRFGYENFNDEGDLGVKGDERRNEKNVMWNLDPYLQTTW
NLTSRWTLDAGARYSTVSFDSQDYYITGSNPDDSGSRRYHKLLPMASLNYAVTPALNTYI
SAGRGFETPTINELSYRTDGKSGLNLGLEPSTSNTVELGSKWRVGNGLVTAAVFQTDTDD
ELIVAQSVGGRSSYTNAGKTRRRGLELSLDQQIEENWRVKMAWTLLDATFRNETCGAGDC
TPAGNRLPGIARNMGYASLEWAPVDGWHAGADVRYMSDIEVNDENSEQAPAYTVASVNAG
YRFNWNKVTLDLFTRVDNLFDRNYVGSVIVNEGNGRYFEPAPGRNYGGGATLSYSFE