Protein Info for ECOLIN_RS20460 in Escherichia coli Nissle 1917
Annotation: 2,3-diketo-L-gulonate TRAP transporter small permease YiaM
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 75% identical to YIAM_ECOLI: 2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM (yiaM) from Escherichia coli (strain K12)
KEGG orthology group: None (inferred from 99% identity to ecp:ECP_3682)MetaCyc: 75% identical to 2,3-diketo-L-gulonate:Na+ symporter - membrane subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-235
Predicted SEED Role
"2,3-diketo-L-gulonate TRAP transporter small permease protein yiaM"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (155 amino acids)
>ECOLIN_RS20460 2,3-diketo-L-gulonate TRAP transporter small permease YiaM (Escherichia coli Nissle 1917) MKRILEGILAIIIAILSCIIFINIILRYGFHTSILSIDELSRLLFVWLTFIGAIVAYMDN SHVQVTFLVEKLSPANQQRVSLLTHTLILLLCLGLAWGAIEKTAQDWSNLSPILGVPIGL MYAAAIPTSLIIALLELRHLYRQFTNTPSRNQQGA