Protein Info for ECOLIN_RS16075 in Escherichia coli Nissle 1917

Annotation: 4Fe-4S dicluster domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 162 PF12800: Fer4_4" amino acids 9 to 22 (14 residues), 12.5 bits, see alignment (E = 8.4e-05) amino acids 84 to 99 (16 residues), 22.6 bits, see alignment (E = 4.7e-08) PF13247: Fer4_11" amino acids 51 to 140 (90 residues), 48.3 bits, see alignment E=5e-16 PF13237: Fer4_10" amino acids 53 to 97 (45 residues), 24.8 bits, see alignment E=8.6e-09 PF12838: Fer4_7" amino acids 55 to 99 (45 residues), 28.9 bits, see alignment E=6.7e-10 PF00037: Fer4" amino acids 82 to 102 (21 residues), 29 bits, see alignment (E = 3.3e-10) PF13187: Fer4_9" amino acids 85 to 137 (53 residues), 33.2 bits, see alignment E=2.2e-11

Best Hits

Swiss-Prot: 98% identical to YGFS_ECOLI: Putative electron transport protein YgfS (ygfS) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 98% identity to eco:b2886)

Predicted SEED Role

"Predicted oxidoreductase, Fe-S subunit"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (162 amino acids)

>ECOLIN_RS16075 4Fe-4S dicluster domain-containing protein (Escherichia coli Nissle 1917)
MKSLIIVNPADCIGCRTCEVACVVAHPSEQELNADIFLPRLKVQRLDSISAPVMCHQCEN
APCVGACPVGALTMGEQVVQANSARCIGCQSCVSACPFGMITIQSLPGDTRQQIVKCDLC
EQREEGPACVESCPTQALQLLTERELRRVRQQRIVASSENPL