Protein Info for Dsui_3474 in Dechlorosoma suillum PS

Annotation: chemotaxis protein histidine kinase-like protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 739 PF01627: Hpt" amino acids 5 to 92 (88 residues), 54.9 bits, see alignment E=1.8e-18 PF02895: H-kinase_dim" amino acids 337 to 395 (59 residues), 44.6 bits, see alignment 3.2e-15 PF02518: HATPase_c" amino acids 444 to 581 (138 residues), 61.6 bits, see alignment E=1.8e-20 PF01584: CheW" amino acids 587 to 715 (129 residues), 95.2 bits, see alignment E=5.6e-31

Best Hits

KEGG orthology group: K03407, two-component system, chemotaxis family, sensor kinase CheA [EC: 2.7.13.3] (inferred from 56% identity to azo:azo0408)

Predicted SEED Role

"Signal transduction histidine kinase CheA (EC 2.7.3.-)" in subsystem Bacterial Chemotaxis or Flagellar motility or Two-component regulatory systems in Campylobacter (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3, 2.7.3.-

Use Curated BLAST to search for 2.7.13.3 or 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QL89 at UniProt or InterPro

Protein Sequence (739 amino acids)

>Dsui_3474 chemotaxis protein histidine kinase-like protein (Dechlorosoma suillum PS)
MSTDDVLQTFVAEARELLLGMEDSLLALERDPRDGEAISATFRAIHTIKGSAGLFSLDQL
VAFAHVAETLLDLVRDGRVAVDGDLIALLLECSDYLGFLINQIAGEEVADAAAQEARRPA
LLARLQACIASSGAPSASQAEGPRQAPPSAAPAAGEVADPVHNDAWHISLRFGPEVLKNG
MDPASFLRYLGTLGEIAHITTLWQQMPAPEAMDAENCYLGFELDFRSEASREAIDSTFDF
VRDDCRITLLPPRSSIDDYLKLIAEAPEGLERLGEILVASGALSQAELERALERQRQAAP
PALGEMLIQEDGIPAPVVQAALEKQTKGRENRSAATRFIRVDAEKLEDLINQVGELVIAG
ASATLLSQRNGDTALIEAMAQVGRHVEEIRDRALSLRMVEIGESFNRFPRVVRDVSRELG
KDIELVITGAETELDKTVVEKIGDPLMHLVRNSMDHGIESIEERLARGKPAQGRLSLHAY
HESGSIVIEVADDGGGLKRDKILAKAMDRGLVAPGQSLTDRDVFNLIFEPGFSTAEQVTN
LSGRGVGMDVVRRNISALRGSIDIESQEGVGTTMRIRLPLTLAIIDGFLIQVADSAFVLP
LDLVQECMELPDGERLQSRGQSSHYLDLRGEALPCLRLRNLLNLEGESSQRENVVIVQYG
NRRAGLVVDRLLGEFQTVIKPLGQIFRHLRGFSGSTILGTGEVALILDVPTLVHDASGRE
ARLLGESNAGQAIGSEQPA