Protein Info for Dsui_3298 in Dechlorosoma suillum PS

Annotation: Kef-type K+ transport system, predicted NAD-binding component

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 566 transmembrane" amino acids 6 to 26 (21 residues), see Phobius details amino acids 33 to 51 (19 residues), see Phobius details amino acids 57 to 77 (21 residues), see Phobius details amino acids 88 to 111 (24 residues), see Phobius details amino acids 117 to 136 (20 residues), see Phobius details amino acids 148 to 168 (21 residues), see Phobius details amino acids 188 to 210 (23 residues), see Phobius details amino acids 230 to 261 (32 residues), see Phobius details amino acids 280 to 297 (18 residues), see Phobius details amino acids 309 to 332 (24 residues), see Phobius details amino acids 341 to 365 (25 residues), see Phobius details amino acids 372 to 392 (21 residues), see Phobius details PF00999: Na_H_Exchanger" amino acids 18 to 389 (372 residues), 185.9 bits, see alignment E=1.1e-58 PF02254: TrkA_N" amino acids 431 to 543 (113 residues), 88.8 bits, see alignment E=3.3e-29

Best Hits

KEGG orthology group: K03455, monovalent cation:H+ antiporter-2, CPA2 family (inferred from 73% identity to bpd:BURPS668_A1723)

Predicted SEED Role

"TrkA-N:Sodium/hydrogen exchanger" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QJG0 at UniProt or InterPro

Protein Sequence (566 amino acids)

>Dsui_3298 Kef-type K+ transport system, predicted NAD-binding component (Dechlorosoma suillum PS)
MPHDISLITTVAAGFGLAMILGFIAARLKIPPLVGYLIAGIIMGPATPGFVADVELAGQL
AEIGVMLLMFGVGLHFSLEDLMNVRRIAVPGAVVQITVATALGTVLAMYWGWSFGGGLVF
GLALSCASTVVLLRALETRGILDSVNGRIAVGWLVVEDLVCVLVLVLMPPLAELLGGSAA
DAHGAGGSLWGTLAVTLAKVGAFIALMLVVGRRLFPRILWAVARTGSRELFTLCVIAAAV
GVAYGSAKLFGVSFALGAFFAGMMMRESDFAHRAAEESLPLRDAFSVLFFVSVGMLFDPQ
VLLQEPGKVLAVAAVVIVGKTVAAILLVLAFRYPLNTALTVGASLAQIGEFSFILAGLGV
ALDLLPKAGQSLILAGALISIAFNSVVFAAIGPARKWALAHSALARRLEMREDPTAALPT
TVEEHFLSGQVVLVGYGRVGRRIAEALDAQKIPYVVAEQHRQVVEKLRERGVPAVSGDAS
DPAVLIQAHIARAGMLVIATPDTLDVRKIVDMARTLNPAIEVVLRTHSEEEAGLLRQESL
GTVFMGEDELAKGMARHVLARMGKGA