Protein Info for Dsui_3183 in Dechlorosoma suillum PS

Annotation: efflux transporter, outer membrane factor lipoprotein, NodT family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 469 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details TIGR01845: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family" amino acids 10 to 464 (455 residues), 396.3 bits, see alignment E=9.7e-123 PF02321: OEP" amino acids 65 to 253 (189 residues), 67.5 bits, see alignment E=6.8e-23 amino acids 283 to 461 (179 residues), 99.4 bits, see alignment E=1.2e-32

Best Hits

Swiss-Prot: 46% identical to ARPC_PSEPU: Antibiotic efflux pump outer membrane protein ArpC (arpC) from Pseudomonas putida

KEGG orthology group: None (inferred from 65% identity to bcm:Bcenmc03_3633)

Predicted SEED Role

"RND efflux system, outer membrane lipoprotein CmeC" in subsystem Multidrug Resistance Efflux Pumps or Multidrug efflux pump in Campylobacter jejuni (CmeABC operon)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QIQ5 at UniProt or InterPro

Protein Sequence (469 amino acids)

>Dsui_3183 efflux transporter, outer membrane factor lipoprotein, NodT family (Dechlorosoma suillum PS)
MRLSPLSLSLLLALGGCSLAPALPKPALPVPDTYGTAPVDEATAKSATASAAAIGWRHMF
GDPRLQRLIEVALEHNRDLRLAVLNVSQVQAQYDIQRSYRVPGVDAGLEGSRQRSSSDGG
NSTAIQETRSASLGISAFEVDLFGRVGSLSEAAFARYLASEHGLRAARISLIGAVAEAYF
AERLAEEQLRLTELTLADWRQSLDLARKLKLAQQSSGLDIAQAEGQVATAEADLESRQRA
LAQARNGLALLLGTEPPADLPPPTPLAQQPVLTQLPPGLPSDLLAHRPDIQQAEQALIAA
NADIGAARAAFFPRLLLTLSVGAISPSFGSLFSGAHQTWAFTPQISQPIFQGGRLRAELR
LAELRRSAAVVEYEKAIQTAFREVRDGLAGSATFGRQIQAQERAVASAERRRELSTLRYR
AGLDSRLELLDAQRQAYASQLGLLELRRDDIRNAIGLYKALGGGRLEQG