Protein Info for Dsui_3161 in Dechlorosoma suillum PS

Annotation: PAS domain S-box/diguanylate cyclase (GGDEF) domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 640 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 53 to 71 (19 residues), see Phobius details TIGR00229: PAS domain S-box protein" amino acids 85 to 210 (126 residues), 55.3 bits, see alignment E=7.4e-19 PF00989: PAS" amino acids 91 to 201 (111 residues), 33.1 bits, see alignment E=9.7e-12 PF08448: PAS_4" amino acids 97 to 205 (109 residues), 71.5 bits, see alignment E=1.4e-23 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 212 to 374 (163 residues), 154.3 bits, see alignment E=2.5e-49 PF00990: GGDEF" amino acids 215 to 371 (157 residues), 175.2 bits, see alignment E=1.9e-55 PF00563: EAL" amino acids 392 to 627 (236 residues), 257.2 bits, see alignment E=2.7e-80

Best Hits

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QIN3 at UniProt or InterPro

Protein Sequence (640 amino acids)

>Dsui_3161 PAS domain S-box/diguanylate cyclase (GGDEF) domain-containing protein (Dechlorosoma suillum PS)
MKPPAPAAPSPNGQAGLVAGLYGLLAALWIALSDRLAALVAGDTAQLTLIQNYKGWAFVA
ITCTLLFFLVRRSLSRLQGSYRALAESEALYESLVQVMPQCLYRMDRESRITFANRALER
HLGKPREAILGHSPREVYPADLAAKYRQDDLRVLQGETLNLIEEMVSLDSEQRKRYIEIV
KTPTYAPDGSINGIQGIFWDITARKSAEEQIEYLAHHDPLTDLPNRVLLRDRFLQAQGQA
ARSANRVAILFLDLDHFKLVNDTLGHPIGDRLLQAVAERLRRGVRETDTISRQGGDEFVI
VLPELADPESAGSIAGKLMEQMHEPVRVNGHRLNVTFSLGIALYPDDGEDFDTLMKKADT
AMYSAKEAGRNTLRFFTAAMNVEAAARLKLQNRLQRALEKEELVLYYQPQFDLASGRILG
TEALLRWRDPERGLVPPGEFIPVAEDTGLIGPIGEWVIGEACRELRRWHEAGATDLTMAV
NLSPVQFRRSRLVEIAARALQENRLPAECLEFELTESLLIREDAAILETLTALKGLGVKL
SIDDFGTGYSSLAYLKRFNVDKLKIDQSFIRELCSNPDDEAIVSAVITMARQLRLRTVAE
GVENAEQATMLRRFDCDEVQGFLFGRPMPAADFQALLGHR