Protein Info for Dsui_2641 in Dechlorosoma suillum PS

Annotation: putative multicopper oxidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 469 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details TIGR01409: Tat (twin-arginine translocation) pathway signal sequence" amino acids 2 to 29 (28 residues), 18.5 bits, see alignment (E = 9.9e-08) PF07731: Cu-oxidase_2" amino acids 84 to 185 (102 residues), 26.2 bits, see alignment E=9.2e-10 amino acids 221 to 336 (116 residues), 80.7 bits, see alignment E=1.3e-26 PF07732: Cu-oxidase_3" amino acids 88 to 195 (108 residues), 115.6 bits, see alignment E=2.1e-37

Best Hits

KEGG orthology group: None (inferred from 79% identity to adk:Alide2_2707)

MetaCyc: 69% identical to MoxA manganese-oxidizing multicopper oxidase (Pedomicrobium sp. ACM 3067)
RXN-11646 [EC: 1.16.3.3]

Predicted SEED Role

"Multicopper oxidase" in subsystem Copper homeostasis

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.16.3.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QNU7 at UniProt or InterPro

Protein Sequence (469 amino acids)

>Dsui_2641 putative multicopper oxidase (Dechlorosoma suillum PS)
MTTRRDFFKNLGMAGGAVAAASVSSVALAALPELVSMDNPDTASPLTPPNGRPYNPVVTL
NGWTLPWRMNNGVKEFHLVAEPVVREIAPGMKAHLWGYNGQSPGPTIEVVEGDRVRIFVT
NRLPEHTTIHWHGQRLPSGMDGVGGLNQKQIPVGKTFVYEFVARRPGTFMYHPHADEMTQ
MAMGMMGFWVTHPKERHPLIETVDRDFCFLLNAYDIDPGSYTPKVNTMLDFNLWTWNSRS
FPGIDSLNVRKGDKVRIRIGNLTMTNHPMHLHGHEFVVSGTDGGPTPIGSRWPEVTTDVA
VGQMRQLDFLADEEGDWAFHCHKSHHTMNAMGHDVPTMIGVDHRGVVKQITDLIPDYMVM
GERGMADMGEMEMPIPDNTLPMMTGQGPYGAVEMGGMFSVLKVRRDQKPGDYRDPGWYKQ
PKNTQAYEWTGPVAAATRSHDAGKGAMRPAGKAQSQEVVVRKPGSHGQH