Protein Info for Dsui_2508 in Dechlorosoma suillum PS

Annotation: Fe-S-cluster-containing hydrogenase subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 241 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF12838: Fer4_7" amino acids 45 to 108 (64 residues), 29.7 bits, see alignment E=2.9e-10 PF13247: Fer4_11" amino acids 86 to 179 (94 residues), 106.2 bits, see alignment E=3.5e-34 PF12797: Fer4_2" amino acids 116 to 136 (21 residues), 25.1 bits, see alignment (E = 4.7e-09) PF00037: Fer4" amino acids 119 to 138 (20 residues), 28.9 bits, see alignment (E = 2.8e-10)

Best Hits

KEGG orthology group: K08358, tetrathionate reductase subunit B (inferred from 66% identity to eba:ebA3055)

Predicted SEED Role

"Tetrathionate reductase subunit B" in subsystem Tetrathionate respiration

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QN21 at UniProt or InterPro

Protein Sequence (241 amino acids)

>Dsui_2508 Fe-S-cluster-containing hydrogenase subunit (Dechlorosoma suillum PS)
MNAQPDLSRRAFFTALPAVTAGLAIPAHAAEEANPHWSMLIDTRRCIACQACTMACSMEN
VSPEGQFRTVVATYAITDQAGKTGLAVLPRLCNHCEEPPCIPVCPVGATFKRPDGIVLVD
GDRCVGCAYCVQACPYDARFVNHHTGKADKCTFCSHRVEAGLLPACVETCVGGARIFGDL
NNPQSDISRRLVAAEGKTSVLKPEAGTTPRVFYIGLEKQLDGRVDGDSTADMMWRPATQG
A