Protein Info for Dsui_2411 in Dechlorosoma suillum PS

Annotation: alanine racemase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00492: alanine racemase
  • amino acids 4 to 361 (358 residues), 339.9 bits, E=8.5e-106
• PF01168: Ala_racemase_N
  • amino acids 9 to 223 (215 residues), 215.5 bits, E=7.7e-68
• PF00842: Ala_racemase_C
  • amino acids 237 to 358 (122 residues), 133 bits, E=4.7e-43

Best Hits

Swiss-Prot: 55% identical to ALR_RALSO: Alanine racemase (alr) from Ralstonia solanacearum (strain GMI1000)

KEGG orthology group: K01775, alanine racemase [EC: 5.1.1.1] (inferred from 65% identity to app:CAP2UW1_2650)

MetaCyc: 49% identical to alanine racemase (Pseudomonas putida)
Alanine racemase. [EC: 5.1.1.1, 5.1.1.10]

Predicted SEED Role

"Alanine racemase (EC 5.1.1.1)" in subsystem Alanine biosynthesis or Pyruvate Alanine Serine Interconversions (EC 5.1.1.1)

MetaCyc Pathways

• anaerobic energy metabolism (invertebrates, cytosol) (7/7 steps found)
• superpathway of anaerobic energy metabolism (invertebrates) (14/17 steps found)
• alanine racemization (1/1 steps found)
• L-alanine degradation I (1/2 steps found)
• L-arginine degradation XIV (oxidative Stickland reaction) (1/6 steps found)
• ansatrienin biosynthesis (1/9 steps found)
• cyclosporin A biosynthesis (2/15 steps found)
• superpathway of L-lysine degradation (9/43 steps found)

KEGG Metabolic Maps

• Alanine and aspartate metabolism
• Cysteine metabolism
• D-Alanine metabolism
• D-Arginine and D-ornithine metabolism
• D-Glutamine and D-glutamate metabolism
• Glycine, serine and threonine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.1.1.1 or 5.1.1.10

Sequence Analysis Tools

See G8QLY1 at UniProt or InterPro

Protein Sequence (363 amino acids)

>Dsui_2411 alanine racemase (Dechlorosoma suillum PS)
MPRPICATIDLGALKHNLAVARQHADQGVAGPARLFAVIKANAYGHGMLPVAQALAGLTD
GFALLDLSEAAKLREAGIREPILLLEGFFQPEDLEAVAELGIIPAVHRLEQLEAIEAAGL
PVKLPVFIKFNTGMHRLGFTAQTWPAAQAFLARSRAIGPVTYMTHFAEADGARGVDWQLE
RFRAWTAGWQGEVSLANSAALLRHKEAVQGWARPGILLYGGSPFAEVSAEELGLKPVMTL
ESEILAVQDVAPGERVGYGGIFEATRPSRIGIVACGYADGYPRHAPPGTPILVDGRPTVT
AGRVSMDMLFCDLTNLPQAGVGSPVTLWGKGMPADAVAAAAGTISYELFCALAPRVPVRW
IGN