Protein Info for Dsui_2374 in Dechlorosoma suillum PS

Annotation: Fe-S protein assembly co-chaperone HscB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 176 TIGR00714: Fe-S protein assembly co-chaperone HscB" amino acids 17 to 168 (152 residues), 108.2 bits, see alignment E=2.1e-35 PF07743: HSCB_C" amino acids 91 to 167 (77 residues), 78.9 bits, see alignment E=1.5e-26

Best Hits

Swiss-Prot: 58% identical to HSCB_AZOSB: Co-chaperone protein HscB homolog (hscB) from Azoarcus sp. (strain BH72)

KEGG orthology group: K04082, molecular chaperone HscB (inferred from 63% identity to dar:Daro_1953)

Predicted SEED Role

"Chaperone protein HscB" in subsystem Protein chaperones

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QLU4 at UniProt or InterPro

Protein Sequence (176 amino acids)

>Dsui_2374 Fe-S protein assembly co-chaperone HscB (Dechlorosoma suillum PS)
MDFNADHFTLFGLPRVFNVDLGVLDARFREAQAQVHPDKFADASEADRRLSMQWATRVNE
AYQALKKPLPRAQYLLHLAGQDVGAENNTAMPVDFLMEQMEWREAVQEARQAGQVDELED
LHFRLRDQIAERYAELGALFDQQADYPAAADLTRRLMFLEKLQHDIDEALVALEDQ