Protein Info for Dsui_2346 in Dechlorosoma suillum PS

Annotation: putative signal transduction protein containing EAL and modified HD-GYP domains

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 455 transmembrane" amino acids 360 to 378 (19 residues), see Phobius details PF08668: HDOD" amino acids 254 to 367 (114 residues), 47 bits, see alignment E=1.1e-16

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QL49 at UniProt or InterPro

Protein Sequence (455 amino acids)

>Dsui_2346 putative signal transduction protein containing EAL and modified HD-GYP domains (Dechlorosoma suillum PS)
MVFGKLIGRLTGQDDTPLQPLPLSALVTTPVVDPAVAAQQRQRAAAEAMLRREEIIDSRN
RLCGYRFSTAGSAAGQTSPQADAPAESAFLAALAGIDLPAFATRRLALVPISRAALAAGG
HLPLRAARSTLLLDVEGSDVEAWLPLLQQARADGCRLALRGLTLLPEHAPLLALADLALL
RLDDYDLTDFQRLARGLKAAAPQLELAADGVPGWPERRMCAAWGFDYCLGPFTVLADCEE
PEGKLDNSRVVLMEMLNLIRAEADLADLGAVAKKDPGIALKVLALANSPAAGLSAPVASL
EQAIMVLGRQRLYRWLTVAMFRVGTPRDRDEALLEVAMTRARFLETVADGVLAKKDCDEL
FLVGLLSLFDVLLAMPLTKVLQLINLADEVTDVLLRSEGPYARFLQLALAVEHGRSAQAA
DIAGELGIDPASLGNTSQLALAWAEEALGISAPDL