Protein Info for Dsui_2301 in Dechlorosoma suillum PS

Annotation: diguanylate cyclase (GGDEF) domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 804 PF00563: EAL" amino acids 101 to 323 (223 residues), 174.7 bits, see alignment E=2.1e-55 PF00990: GGDEF" amino acids 486 to 585 (100 residues), 51.5 bits, see alignment E=1e-17 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 488 to 626 (139 residues), 56.3 bits, see alignment E=1.6e-19

Best Hits

KEGG orthology group: None (inferred from 53% identity to mmb:Mmol_1064)

Predicted SEED Role

"FIG00799083: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QL05 at UniProt or InterPro

Protein Sequence (804 amino acids)

>Dsui_2301 diguanylate cyclase (GGDEF) domain-containing protein (Dechlorosoma suillum PS)
MCLFLKYDGPYVPSLWPMLGGRQVDRHVWRFDAADNAALDQLMESLAAETNRETLKETLA
VHCDQSEASLGLVPTLQLALPFNTLYARRLHAWMLGDLRPHVRMHFQPLVDMTQDGQVFA
LEALCRLEHPQGRLLSGAEAFHLAGQLGREADLDLECQFMALEAKANRIPAGTPLFLNVL
PQNMLHSQWTQRMVEHLNRLGIDRREVVIEVVESERVDPNVLADSCEALRTLGFRIALDD
MGAGFNGLSTLAAVRADFIKVDRSIVHGAQGSRVRSVLLEAIVSMAQRLGATVIAEGLER
PEDVNFVRDMGISYAQGFYFAQPQLLTEPEVAPLPRQDDSCRSRPRDRFQLTDLMDPWQS
IDLRASVPEARQIFQEAPSLPLAIVTDQGQPIGLVRRGKVLSAAARTLGKLCEPVARNLP
HRLTTPALARILYHDRKDSDPWVVTSNEGQYLGVIHPMTLIAQMLARRENGSNLHPLSHL
PTGPSLRHTLESRLAENQTVCLVYIDLDHFKAYNDRYGFIRGDAMIRTLAELLRHTFVGR
PECLLGHIGGDDFILVMESMGPGLTDELLSIMEQFQALASHLYDHEDIARGHFLTDDGLA
HPIASISVAVVNASTGRLANAVAAAERAAALKKVGKVEQGSVIVVEGVPPAMIKQQHNHG
LGLWKENAIAALADFIGAPRSRDPHALDAWFRSYPFFEMVFELDGAGVQRYPNWINPDMY
GRIKAGGVGVDRSEQPYFAHVAEGGQPYVSEIYLSSATEDFCITLAVPLREGSVIDGVLV
ADINISSMASLTRRFHLDHEAQAA