Protein Info for Dsui_2299 in Dechlorosoma suillum PS

Annotation: flavin-dependent dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 548 PF13450: NAD_binding_8" amino acids 12 to 57 (46 residues), 26 bits, see alignment 2.8e-09 PF21162: ETFQO_UQ-bd" amino acids 211 to 304 (94 residues), 149.3 bits, see alignment E=1.1e-47 PF05187: Fer4_ETF_QO" amino acids 443 to 545 (103 residues), 176.6 bits, see alignment E=3.5e-56

Best Hits

Swiss-Prot: 52% identical to ETFQO_ORYSJ: Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (Os10g0516300) from Oryza sativa subsp. japonica

KEGG orthology group: K00311, electron-transferring-flavoprotein dehydrogenase [EC: 1.5.5.1] (inferred from 81% identity to dar:Daro_1936)

Predicted SEED Role

"Electron transfer flavoprotein-ubiquinone oxidoreductase (EC 1.5.5.1)" in subsystem Acetyl-CoA fermentation to Butyrate or Anaerobic respiratory reductases (EC 1.5.5.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.5.5.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QL03 at UniProt or InterPro

Protein Sequence (548 amino acids)

>Dsui_2299 flavin-dependent dehydrogenase (Dechlorosoma suillum PS)
MQRESMEYDVLIVGGGPAGLAAAIRLKQLAAANGQECGVCLIEKGSEIGAHILSGAVMDP
KALTELIPDWKEQGAPLNAPVSEDRFFILSEDGGWQVPNGLLPGCFHNEGNYVISLGNVC
RWLGQQAENLGVEIYPGFAGAEVLYNEDGSVKGVATGDMGRLKDGSEGPAFQLGMELHAK
YTLFAEGCRGHLGKQIQAKFNLASDADPQVYGIGIKELWEIKPEKHQTGLVVHTGGWPMD
NDTYGGGFLYHMEDNLVSVGFVVGLGYDNPHLSPYEEMQRFKTHPKIREFLEGGKRVSYG
ARAITAGGLQSLPKLTFPGGVLIGDDAGFLNASRIKGSHCAIKSGSLAAEACFEALAAER
SFDELTAYPEKFKASWLYEELYKARNFKPWMSKGLHWGGFMFGVDQKLFGGKAPWTLHHS
GPDHLKLKKAKDCTPIAYPKPDGVLTFDRLSSVFLSNTNHEEDEPCHLQLKDAAVPIQVN
LAQYDAPEQRYCPAGVYEILREADGSNPRLQINAQNCVHCKTCDIKDPTQNITWVVPQGG
EGPNYPNM