Protein Info for Dsui_2160 in Dechlorosoma suillum PS

Annotation: PAS domain S-box/diguanylate cyclase (GGDEF) domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 651 transmembrane" amino acids 25 to 47 (23 residues), see Phobius details amino acids 53 to 71 (19 residues), see Phobius details TIGR00229: PAS domain S-box protein" amino acids 94 to 211 (118 residues), 59.7 bits, see alignment E=3e-20 PF13188: PAS_8" amino acids 94 to 132 (39 residues), 28.3 bits, see alignment 4.2e-10 PF00989: PAS" amino acids 94 to 200 (107 residues), 42.2 bits, see alignment E=2.5e-14 PF08448: PAS_4" amino acids 97 to 202 (106 residues), 32 bits, see alignment E=4.4e-11 PF13426: PAS_9" amino acids 101 to 202 (102 residues), 54.7 bits, see alignment E=3.9e-18 PF08447: PAS_3" amino acids 114 to 197 (84 residues), 35.6 bits, see alignment E=3.3e-12 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 213 to 374 (162 residues), 138 bits, see alignment E=2.5e-44 PF00990: GGDEF" amino acids 215 to 372 (158 residues), 170 bits, see alignment E=1.3e-53 PF00563: EAL" amino acids 393 to 628 (236 residues), 252.2 bits, see alignment E=1.6e-78

Best Hits

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QJQ2 at UniProt or InterPro

Protein Sequence (651 amino acids)

>Dsui_2160 PAS domain S-box/diguanylate cyclase (GGDEF) domain-containing protein (Dechlorosoma suillum PS)
MSPAPKSSAPACCANPLLRPGHRQAWPLVLLYLCAGGALLAVLQGAAGLSDGGAAVLVLG
SSAAVLYLLLYRSGTPRELAACRDYVHRLNLASAVFSAAREGIVVTDLEGRVEAVNPAFC
QITGYGEAELQGFNLRLLKSGRQDGAFYRQLWRDLLESGHWQGEIWNRRKNGETYPQWLT
ISTVRDEAHQPVSYVGVFLDLSPIRRSEQKLLHLAHHDPLTDLPNRTLFLARLEHALSLS
AREGGSGAVLFLDLDRFKDVNDSLGHPTGDRLLCAVAERLRPCLRESDTLARLGGDEFLL
LLETAATPERAAVVAEKLLEQLAAPFRLDDRSEVYVGASIGICLYPADGDNATTLIQHAD
SALYQAKAAGRHTFRFYSEAQTRQADARLALEAALRRGLEKEEFLLYYQPQVDLRTASLE
GVEALVRWRLPGGELVPPARFIPLAEETGLILPLGEWVLRQACRQMQQWVARGLPIRRVA
VNLSSRQFRQADLLQRINAILAETGLAPRYLELEITESLLMDNSAQVDAKLEALEAMGIR
LAIDDFGTGYSSLSYLKRFPLHTLKLDRSFIRDIADDPVSSNIVASIIELGQHLDMDILA
EGVETDQQRGILLQNGCRTCQGYLFSHPLPAEELEARWLRAAADLGVPPRN