Protein Info for Dsui_1986 in Dechlorosoma suillum PS

Annotation: sulfite reductase, beta subunit (hemoprotein)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF03460: NIR_SIR_ferr
  • amino acids 53 to 111 (59 residues), 66.6 bits, 1.3e-22
  • amino acids 348 to 398 (51 residues), 45.2 bits, 6.4e-16
• PF01077: NIR_SIR
  • amino acids 119 to 273 (155 residues), 153.2 bits, E=4.1e-49
  • amino acids 413 to 554 (142 residues), 54.7 bits, E=8.3e-19

Best Hits

KEGG orthology group: K00381, sulfite reductase (NADPH) hemoprotein beta-component [EC: 1.8.1.2] (inferred from 74% identity to dar:Daro_2912)

Predicted SEED Role

"Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2)" in subsystem Cysteine Biosynthesis (EC 1.8.1.2)

MetaCyc Pathways

• superpathway of sulfate assimilation and cysteine biosynthesis (8/9 steps found)
• superpathway of L-methionine biosynthesis (by sulfhydrylation) (10/12 steps found)
• assimilatory sulfate reduction III (3/3 steps found)
• superpathway of sulfur amino acid biosynthesis (Saccharomyces cerevisiae) (8/10 steps found)
• assimilatory sulfate reduction I (3/4 steps found)

KEGG Metabolic Maps

• Sulfur metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.8.1.2

Use Curated BLAST to search for 1.8.1.2

Sequence Analysis Tools

See G8QI04 at UniProt or InterPro

Protein Sequence (558 amino acids)

>Dsui_1986 sulfite reductase, beta subunit (hemoprotein) (Dechlorosoma suillum PS)
MYRYDNYDHALVQERVAQFRDQVRRWKAGELSDEEFRPLRLQNGLYIQRHAPMFRVAVPY
GMLSSAQLRRLAKIARDYDKGYGHFTTRHNLQFNWIPLERVPDALAELAEVEMHAIQTSG
NCIRNVTTDQFAGVAADEILDPRPLCELLRQWSTFHPEFAFLPRKFKIAVNGALEDRALT
WFHDIGLHIRKNEAGEVGFRVIVGGGLGRTPIRGQVVREFLPWQDILTYNEAILRVYNRY
GRRDNAYKARIKILVQALGVEKFAEQVEAEWAHLKGGPATITQAEYDRVAAFFNPPAYAQ
LPAIDDGFVQAQAEQPAFARWVERNVRPHRVPGYAAVTLSLKKPGTAPGDVSDVQMDRVA
DLADRYSFGEVRVTHEQNLVLADVRQDELQALWQDAKAAALATPNIGLITDMICCPGGDF
CDLANAKSIPIANAIQAKFEDLDYLYDIGDIELNISGCMNSCGHHHVGHIGVLGVDKGNE
EWYQITLGGRQGNNAHLGKVIGPSFPADEVAGVVEKLIRVYLDNRHEDELFIDTLDRLGV
EPFKDKVYGDRLKGKKAA