Protein Info for Dsui_1872 in Dechlorosoma suillum PS

Annotation: RND family efflux transporter, MFP subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 419 signal peptide" amino acids 1 to 36 (36 residues), see Phobius details TIGR01730: efflux transporter, RND family, MFP subunit" amino acids 47 to 361 (315 residues), 242.6 bits, see alignment E=2.6e-76 PF16576: HlyD_D23" amino acids 71 to 281 (211 residues), 43.8 bits, see alignment E=3.7e-15 PF13533: Biotin_lipoyl_2" amino acids 74 to 118 (45 residues), 31 bits, see alignment 3.4e-11 PF00529: CusB_dom_1" amino acids 205 to 348 (144 residues), 27.7 bits, see alignment E=4.3e-10

Best Hits

KEGG orthology group: K03585, membrane fusion protein (inferred from 68% identity to dar:Daro_2160)

Predicted SEED Role

"RND efflux system, membrane fusion protein CmeA" in subsystem Multidrug Resistance Efflux Pumps or Multidrug efflux pump in Campylobacter jejuni (CmeABC operon)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QHA3 at UniProt or InterPro

Protein Sequence (419 amino acids)

>Dsui_1872 RND family efflux transporter, MFP subunit (Dechlorosoma suillum PS)
MSSTQQSPAPLLRLRPAAAALVLALGLAACSGENAAPQGGAPQALPVTVLEMQPQNLPAS
LELMAQTEGAKETEVRARVGGILMKRLYQEGALVKAGQPLFQIDRAPYEIALAEAKAKAE
QTAREEGRLKGLLARQAVSQKEYDDAASNNAIAQAALRQAQLNLSWTTVTAPVSGTSGRA
VKSEGNLINTSDASLLTSVYQANPMWVRFGLSESDTANLPGGQLKAEMVSGVELILPDGS
VYDKPGKINFLASTIDTTLGTQQLRAEFDNSDGKLLPGQFVRVRLLTGNREGVFLVPQAA
VMQTEQARLVMVVDAESKVAPRPVQTAEWRGKDWVITGGLKAGDKVIVDNLMKARPGAPV
APHGPQAAPGAPGAAPGTPAQGQPAAAKPADAAPAAAPAKGAEGDAAKTPAQPAAQGKQ