Protein Info for Dsui_1817 in Dechlorosoma suillum PS

Annotation: anaerobic dehydrogenase, typically selenocysteine-containing

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 921 PF04879: Molybdop_Fe4S4" amino acids 11 to 58 (48 residues), 70.2 bits, see alignment 2.4e-23 PF00384: Molybdopterin" amino acids 71 to 497 (427 residues), 245.1 bits, see alignment E=2.2e-76 PF01568: Molydop_binding" amino acids 600 to 709 (110 residues), 81.4 bits, see alignment E=1e-26 PF04324: Fer2_BFD" amino acids 866 to 912 (47 residues), 36 bits, see alignment 1.4e-12

Best Hits

KEGG orthology group: K00372, nitrate reductase catalytic subunit [EC: 1.7.99.4] (inferred from 68% identity to app:CAP2UW1_2772)

Predicted SEED Role

"Assimilatory nitrate reductase large subunit (EC:1.7.99.4)" in subsystem Nitrate and nitrite ammonification (EC 1.7.99.4)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.7.99.4

Use Curated BLAST to search for 1.7.99.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QGQ7 at UniProt or InterPro

Protein Sequence (921 amino acids)

>Dsui_1817 anaerobic dehydrogenase, typically selenocysteine-containing (Dechlorosoma suillum PS)
MPNESHFPPSVTPSTCCYCGTGCGVLIDSRDGRITDVRGDPEHPANQGRLCAKGATLHLT
AAPGTRQANRALYPEVRTRRDQPRQRVSWEQAMAVAARRFAAVIAEHGPEAVAFYVSGQL
LTEDYYVFNKLVKGFIGSNNIDTNSRLCMSSAASGYKLTLGVDAPPNCYEDIGLAQCLFI
TGANPAAAHPIVFRRIEDAREANPELKIIVADPRRSETAAIADLHLALKPGTDIALYNAM
LHVLLAENLVDRDYIAAHTEGFAALETIAADYSPAVAAQICGIPAEDIVQAARWFGLSKA
SLSLWCQGLNQSRHGSHNNAALIHLHLATGHIGRPGAGPFSLTGQPNAMGGREVGGMANL
LSAHRDLGNAEHRAEVARFWGVPEVPAKPGLTAVQLFEAVGRGEVKALWIACTNPAHSLP
DQARVRAALETAEFVVLQEAYGDTDTAAYADLLLPAASWGEKEGTVTNSERRISRVRAAV
APAGEARADWAIAVDFAHRLGDELGRGDEARRLFPYRRPEAIFNEHRDSTRGRDLDITGL
SYGLLEQRGPQLWPFPAGAEAGLPRLYADGRFPTPSGRARFVPVQHQEVAEPTDVDQPIS
LLSGRLRDQWHGMSRTGTVPRLFHGAEEAVLAMHPCDLRHRGLEDGDLARVSNGRDSLVL
RVAAVAGLKKGRAWLPMHWGSRFMHGAGANAFTGPACDPISLQPELKHAPVQVEKADLPW
PLAVVRAGEGPDALASSLALLQRARRLLPRFPYASVGLYGRGQPLVVFRAAAEAPLDEAQ
IREIDALFDLEREEGAIVYADRRRHIGKRALARDGHLLGVRLAGETQALAWLKDAISDDV
LDPDLLRWAVAPISTPPAKLLRASPVVCKCADITQAQIEAGIARGLDLDGLQNELKCGTF
CGGCLPEVKKIIVAKTSPQAA