Protein Info for Dsui_1690 in Dechlorosoma suillum PS

Annotation: cAMP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 219 PF00027: cNMP_binding" amino acids 36 to 123 (88 residues), 99 bits, see alignment E=1.9e-32 PF13545: HTH_Crp_2" amino acids 155 to 217 (63 residues), 57.5 bits, see alignment E=1.6e-19 PF00325: Crp" amino acids 177 to 207 (31 residues), 40.7 bits, see alignment 2.4e-14

Best Hits

Swiss-Prot: 38% identical to VFR_PSEAE: Cyclic AMP receptor-like protein (vfr) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K10914, CRP/FNR family transcriptional regulator, cyclic AMP receptor protein (inferred from 68% identity to app:CAP2UW1_2298)

Predicted SEED Role

"cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases" in subsystem cAMP signaling in bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QFL1 at UniProt or InterPro

Protein Sequence (219 amino acids)

>Dsui_1690 cAMP-binding protein (Dechlorosoma suillum PS)
MQVGRGLSLATLRGLPMFERVPDSELEHLARVSTYRKVTRGTTIVRAGDVTDSLYILISG
SIKVLNSDEEGREVILAILGTGEFFGEMGLLDGEPRSANVVALEVCEVLIIAKAEFRRLL
TEHVDLTFYLLRSLVQRLREADRKIESLALMDVFGRVAKLLLEFSEMQEGRRIVTRKLTK
QDIAKMIGASREMVSRVMKDLETSGYIEVQDGRIVLHEI